LEXICON PHARMACEUTICALS INC

Ticker: LXRX CUSIP: 528872302 Class: COM NEW

LOOMIS SAYLES & CO L P's Holding History (CIK: 0000312348)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017

Shares 986,386 Value ($000) $12,123 Avg Close $14.77 Range $11.80 - $17.29

Q2 2017

Shares 883,349 Value ($000) $14,531 Avg Close $15.48 Range $13.48 - $18.00

Q1 2017

Shares 913,833 Value ($000) $13,104 Avg Close $14.84 Range $13.41 - $17.48

Q4 2016

Shares 838,372 Value ($000) $11,595 Avg Close $16.04 Range $13.71 - $19.50

Q3 2016

Shares 881,449 Value ($000) $15,928 Avg Close $16.09 Range $13.73 - $19.62

Q2 2016

Shares 1,074,204 Value ($000) $15,415 Avg Close $13.56 Range $11.52 - $15.17

Q1 2016

Shares 1,107,395 Value ($000) $13,233 Avg Close $10.48 Range $7.65 - $13.45

Q4 2015

Shares 1,110,397 Value ($000) $14,779 Avg Close $12.29 Range $9.22 - $14.50

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2017	986,386	$12,123	$14.77	$11.80 - $17.29
Q2 2017	883,349	$14,531	$15.48	$13.48 - $18.00
Q1 2017	913,833	$13,104	$14.84	$13.41 - $17.48
Q4 2016	838,372	$11,595	$16.04	$13.71 - $19.50
Q3 2016	881,449	$15,928	$16.09	$13.73 - $19.62
Q2 2016	1,074,204	$15,415	$13.56	$11.52 - $15.17
Q1 2016	1,107,395	$13,233	$10.48	$7.65 - $13.45
Q4 2015	1,110,397	$14,779	$12.29	$9.22 - $14.50