LIGAND PHARMACEUTICALS INC

Ticker: LGND CUSIP: 53220K504 Class: Common Stock

VILLERE ST DENIS J & CO LLC's Holding History (CIK: 0001113629)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 202,452 Value ($000) $38,278 Avg Close $192.14 Range $175.56 - $212.49

Q3 2025

Shares 279,950 Value ($000) $49,590 Avg Close $148.66 Range $111.72 - $177.81

Q2 2025

Shares 287,120 Value ($000) $32,640 Avg Close $106.88 Range $93.58 - $118.58

Q1 2025

Shares 288,827 Value ($000) $30,367 Avg Close $113.09 Range $102.79 - $125.17

Q4 2024

Shares 287,044 Value ($000) $30,757 Avg Close $113.04 Range $97.78 - $129.90

Q3 2024

Shares 474,858 Value ($000) $47,529 Avg Close $100.67 Range $81.74 - $112.13

Q2 2024

Shares 483,913 Value ($000) $40,775 Avg Close $79.57 Range $67.72 - $88.73

Q1 2024

Shares 490,752 Value ($000) $35,874 Avg Close $73.72 Range $67.53 - $94.57

Q4 2023

Shares 428,051 Value ($000) $30,571 Avg Close $59.01 Range $49.24 - $73.74

Q3 2023

Shares 438,161 Value ($000) $26,255 Avg Close $65.82 Range $57.94 - $72.97

Q2 2023

Shares 479,447 Value ($000) $34,568 Avg Close $75.03 Range $68.87 - $85.70

Q1 2023

Shares 480,807 Value ($000) $35,368 Avg Close $71.09 Range $64.75 - $78.00

Q4 2022

Shares 483,347 Value ($000) $32 Avg Close $65.02 Range $52.61 - $83.95

Q3 2022

Shares 491,107 Value ($000) $42,289 Avg Close $58.78 Range $47.79 - $68.00

Q2 2022

Shares 496,028 Value ($000) $44,255 Avg Close $56.75 Range $45.27 - $73.85

Q1 2022

Shares 510,843 Value ($000) $57,464 Avg Close $72.55 Range $55.21 - $97.49

Q4 2021

Shares 518,988 Value ($000) $80,162 Avg Close $92.38 Range $78.60 - $106.04

Q3 2021

Shares 564,349 Value ($000) $78,625 Avg Close $77.34 Range $63.64 - $91.19

Q2 2021

Shares 594,380 Value ($000) $77,976 Avg Close $83.18 Range $68.78 - $99.79

Q1 2021

Shares 537,028 Value ($000) $81,869 Avg Close $94.53 Range $61.52 - $137.09

Q4 2020

Shares 642,073 Value ($000) $63,854 Avg Close $57.01 Range $48.82 - $67.37

Q3 2020

Shares 663,383 Value ($000) $63,233 Avg Close $68.23 Range $54.55 - $79.73

Q2 2020

Shares 647,668 Value ($000) $72,441 Avg Close $63.40 Range $41.95 - $77.96

Q1 2020

Shares 635,758 Value ($000) $46,232 Avg Close $56.68 Range $35.71 - $76.16

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	202,452	$38,278	$192.14	$175.56 - $212.49
Q3 2025	279,950	$49,590	$148.66	$111.72 - $177.81
Q2 2025	287,120	$32,640	$106.88	$93.58 - $118.58
Q1 2025	288,827	$30,367	$113.09	$102.79 - $125.17
Q4 2024	287,044	$30,757	$113.04	$97.78 - $129.90
Q3 2024	474,858	$47,529	$100.67	$81.74 - $112.13
Q2 2024	483,913	$40,775	$79.57	$67.72 - $88.73
Q1 2024	490,752	$35,874	$73.72	$67.53 - $94.57
Q4 2023	428,051	$30,571	$59.01	$49.24 - $73.74
Q3 2023	438,161	$26,255	$65.82	$57.94 - $72.97
Q2 2023	479,447	$34,568	$75.03	$68.87 - $85.70
Q1 2023	480,807	$35,368	$71.09	$64.75 - $78.00
Q4 2022	483,347	$32	$65.02	$52.61 - $83.95
Q3 2022	491,107	$42,289	$58.78	$47.79 - $68.00
Q2 2022	496,028	$44,255	$56.75	$45.27 - $73.85
Q1 2022	510,843	$57,464	$72.55	$55.21 - $97.49
Q4 2021	518,988	$80,162	$92.38	$78.60 - $106.04
Q3 2021	564,349	$78,625	$77.34	$63.64 - $91.19
Q2 2021	594,380	$77,976	$83.18	$68.78 - $99.79
Q1 2021	537,028	$81,869	$94.53	$61.52 - $137.09
Q4 2020	642,073	$63,854	$57.01	$48.82 - $67.37
Q3 2020	663,383	$63,233	$68.23	$54.55 - $79.73
Q2 2020	647,668	$72,441	$63.40	$41.95 - $77.96
Q1 2020	635,758	$46,232	$56.68	$35.71 - $76.16