LOXO ONCOLOGY INC

CUSIP: 548862101 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 175,000 Value ($000) $24,512 Avg Close — Range —
Q3 2018
Shares 175,000 Value ($000) $29,895 Avg Close — Range —
Q2 2018
Shares 175,000 Value ($000) $30,359 Avg Close — Range —
Q1 2018
Shares 179,400 Value ($000) $20,697 Avg Close — Range —
Q4 2017
Shares 176,300 Value ($000) $14,841 Avg Close — Range —
Q3 2017
Shares 130,000 Value ($000) $11,975 Avg Close — Range —
Q2 2017
Shares 130,000 Value ($000) $10,425 Avg Close — Range —
Q1 2017
Shares 130,000 Value ($000) $5,470 Avg Close — Range —
Q4 2016
Shares 125,000 Value ($000) $4,014 Avg Close — Range —
Q3 2016
Shares 110,000 Value ($000) $2,880 Avg Close — Range —