LYRA THERAPEUTICS INC

Ticker: LYRA CUSIP: 55234L204 Class: COM NEW

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (3)

Artia Global Partners LP
Value ($000) $27 Shares 8,756
DRW Securities, LLC
Value ($000) $52 Shares 16,812
Global Retirement Partners, LLC
Value ($000) $0 Shares 15

Increased Positions (6)

SABBY MANAGEMENT, LLC
Value ($000) $539 (-35.2%) Shares 175,158 (+37.2%)
Tower Research Capital LLC (TRC)
Value ($000) $7 (+93.6%) Shares 2,191 (+310.3%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $38 (-47.9%) Shares 12,249 (+11.5%)
BlackRock, Inc.
Value ($000) $7 (-33.1%) Shares 2,394 (+41.7%)
ROYAL BANK OF CANADA
Value ($000) $6 (-33.3%) Shares 1,953 (+47.4%)
BANK OF AMERICA CORP /DE/
Value ($000) $1 (+429.1%) Shares 201 (+1016.7%)

Decreased Positions (6)

UBS Group AG
Value ($000) $2 (-92.0%) Shares 675 (-83.1%)
MORGAN STANLEY
Value ($000) $1 (-87.7%) Shares 334 (-73.8%)
CITIGROUP INC
Value ($000) $0 (-99.8%) Shares 3 (-99.6%)
EverSource Wealth Advisors, LLC
Value ($000) $1 (-53.8%) Shares 338 (-2.0%)
IFP Advisors, Inc
Value ($000) $0 (-76.9%) Shares 1 (-50.0%)
CWM, LLC
Value ($000) $0 Shares 1 (-95.8%)

Exited Positions (6)

PERCEPTIVE ADVISORS LLC
Value ($000) $1,498 Shares 229,382
VANGUARD GROUP INC
Value ($000) $189 Shares 28,754
CITADEL ADVISORS LLC
Value ($000) $128 Shares 19,484
Signature Resources Capital Management, LLC
Value ($000) $3 Shares 400
FMR LLC
Value ($000) $3 Shares 406
Fortitude Family Office, LLC
Value ($000) $1 Shares 96