MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

Jefferies Financial Group Inc.'s Holding History (CIK: 0000096223)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,300 Value ($000) $1,339 Avg Close $510.76 Range $393.61 - $615.00

Q4 2024

Shares 250 Value ($000) $77 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 352 Value ($000) $75 Avg Close $255.83 Range $208.94 - $298.00

Q2 2023

Shares 274 Value ($000) $63 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 1,353 Value ($000) $328 Avg Close $272.48 Range $222.87 - $313.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,300	$1,339	$510.76	$393.61 - $615.00
Q4 2024	250	$77	$281.26	$200.63 - $368.29
Q3 2024	352	$75	$255.83	$208.94 - $298.00
Q2 2023	274	$63	$270.85	$192.22 - $322.67
Q1 2023	1,353	$328	$272.48	$222.87 - $313.93