MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

DIMENSIONAL FUND ADVISORS LP's Holding History (CIK: 0000354204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 19,321 Value ($000) $11,251 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 5,799 Value ($000) $2,660 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 3,870 Value ($000) $1,171 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 3,844 Value ($000) $1,273 Avg Close $328.59 Range $266.44 - $377.46

Q2 2023

Shares 16,345 Value ($000) $3,776 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 16,301 Value ($000) $3,949 Avg Close $272.48 Range $222.87 - $313.93

Q4 2022

Shares 13,079 Value ($000) $4 Avg Close $97.80 Range $57.21 - $315.45

Q3 2022

Shares 45,995 Value ($000) $2,989 Avg Close $69.48 Range $59.47 - $82.00

Q2 2022

Shares 169,294 Value ($000) $12,117 Avg Close $73.50 Range $57.15 - $100.90

Q1 2022

Shares 216,197 Value ($000) $21,214 Avg Close $84.31 Range $52.33 - $105.93

Q4 2021

Shares 202,312 Value ($000) $17,144 Avg Close $82.16 Range $68.56 - $102.42

Q3 2021

Shares 174,412 Value ($000) $13,917 Avg Close $86.38 Range $77.60 - $105.72

Q2 2021

Shares 169,172 Value ($000) $16,479 Avg Close $118.38 Range $95.21 - $142.62

Q1 2021

Shares 172,511 Value ($000) $20,178 Avg Close $116.59 Range $105.16 - $131.99

Q4 2020

Shares 188,830 Value ($000) $20,992 Avg Close $122.23 Range $107.55 - $137.28

Q3 2020

Shares 199,764 Value ($000) $23,718 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 199,020 Value ($000) $22,531 Avg Close $98.34 Range $56.82 - $127.25

Q1 2020

Shares 197,678 Value ($000) $13,199 Avg Close $83.31 Range $60.86 - $94.74

Q4 2019

Shares 185,544 Value ($000) $16,904 Avg Close $96.98 Range $82.31 - $121.21

Q3 2019

Shares 115,322 Value ($000) $9,943 Avg Close $93.82 Range $82.39 - $108.37

Q2 2019

Shares 89,176 Value ($000) $9,346 Avg Close $107.12 Range $89.83 - $145.16

Q1 2019

Shares 17,270 Value ($000) $2,164 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 7,662 Value ($000) $862 Avg Close $154.76 Range $91.56 - $222.29

Q3 2018

Shares 11,305 Value ($000) $2,420 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 4,793 Value ($000) $1,340 Avg Close $175.60 Range $98.81 - $325.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	19,321	$11,251	$510.76	$393.61 - $615.00
Q3 2025	5,799	$2,660	$373.08	$284.02 - $460.22
Q2 2025	3,870	$1,171	$297.95	$265.00 - $349.00
Q1 2025	3,844	$1,273	$328.59	$266.44 - $377.46
Q2 2023	16,345	$3,776	$270.85	$192.22 - $322.67
Q1 2023	16,301	$3,949	$272.48	$222.87 - $313.93
Q4 2022	13,079	$4	$97.80	$57.21 - $315.45
Q3 2022	45,995	$2,989	$69.48	$59.47 - $82.00
Q2 2022	169,294	$12,117	$73.50	$57.15 - $100.90
Q1 2022	216,197	$21,214	$84.31	$52.33 - $105.93
Q4 2021	202,312	$17,144	$82.16	$68.56 - $102.42
Q3 2021	174,412	$13,917	$86.38	$77.60 - $105.72
Q2 2021	169,172	$16,479	$118.38	$95.21 - $142.62
Q1 2021	172,511	$20,178	$116.59	$105.16 - $131.99
Q4 2020	188,830	$20,992	$122.23	$107.55 - $137.28
Q3 2020	199,764	$23,718	$108.57	$98.65 - $125.06
Q2 2020	199,020	$22,531	$98.34	$56.82 - $127.25
Q1 2020	197,678	$13,199	$83.31	$60.86 - $94.74
Q4 2019	185,544	$16,904	$96.98	$82.31 - $121.21
Q3 2019	115,322	$9,943	$93.82	$82.39 - $108.37
Q2 2019	89,176	$9,346	$107.12	$89.83 - $145.16
Q1 2019	17,270	$2,164	$124.30	$102.43 - $148.18
Q4 2018	7,662	$862	$154.76	$91.56 - $222.29
Q3 2018	11,305	$2,420	$250.94	$193.57 - $315.00
Q2 2018	4,793	$1,340	$175.60	$98.81 - $325.98