MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM's Holding History (CIK: 0000919079)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 31,286 Value ($000) $18,219 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 24,097 Value ($000) $11,052 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 27,583 Value ($000) $8,348 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 27,580 Value ($000) $9,135 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 21,310 Value ($000) $6,576 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 22,295 Value ($000) $4,731 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 22,262 Value ($000) $6,237 Avg Close $238.04 Range $189.00 - $295.50

Q1 2024

Shares 20,190 Value ($000) $5,392 Avg Close $235.62 Range $168.25 - $299.98

Q4 2023

Shares 20,190 Value ($000) $4,672 Avg Close $174.99 Range $119.76 - $245.31

Q3 2023

Shares 24,858 Value ($000) $3,630 Avg Close $188.22 Range $143.75 - $239.76

Q2 2023

Shares 19,637 Value ($000) $4,536 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 12,938 Value ($000) $3,134 Avg Close $272.48 Range $222.87 - $313.93

Q1 2021

Shares 17,900 Value ($000) $2,094 Avg Close $116.59 Range $105.16 - $131.99

Q4 2020

Shares 17,900 Value ($000) $1,990 Avg Close $122.23 Range $107.55 - $137.28

Q3 2020

Shares 18,300 Value ($000) $2,173 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 17,700 Value ($000) $2,005 Avg Close $98.34 Range $56.82 - $127.25

Q1 2020

Shares 16,300 Value ($000) $1,088 Avg Close $83.31 Range $60.86 - $94.74

Q4 2019

Shares 16,500 Value ($000) $1,503 Avg Close $96.98 Range $82.31 - $121.21

Q3 2019

Shares 14,000 Value ($000) $1,207 Avg Close $93.82 Range $82.39 - $108.37

Q2 2019

Shares 6,238 Value ($000) $654 Avg Close $107.12 Range $89.83 - $145.16

Q1 2019

Shares 5,438 Value ($000) $681 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 5,538 Value ($000) $624 Avg Close $154.76 Range $91.56 - $222.29

Q3 2018

Shares 10,718 Value ($000) $2,295 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 5,908 Value ($000) $1,652 Avg Close $175.60 Range $98.81 - $325.98

Q1 2018

Shares 3,868 Value ($000) $452 Avg Close $123.44 Range $90.56 - $154.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	31,286	$18,219	$510.76	$393.61 - $615.00
Q3 2025	24,097	$11,052	$373.08	$284.02 - $460.22
Q2 2025	27,583	$8,348	$297.95	$265.00 - $349.00
Q1 2025	27,580	$9,135	$328.59	$266.44 - $377.46
Q4 2024	21,310	$6,576	$281.26	$200.63 - $368.29
Q3 2024	22,295	$4,731	$255.83	$208.94 - $298.00
Q2 2024	22,262	$6,237	$238.04	$189.00 - $295.50
Q1 2024	20,190	$5,392	$235.62	$168.25 - $299.98
Q4 2023	20,190	$4,672	$174.99	$119.76 - $245.31
Q3 2023	24,858	$3,630	$188.22	$143.75 - $239.76
Q2 2023	19,637	$4,536	$270.85	$192.22 - $322.67
Q1 2023	12,938	$3,134	$272.48	$222.87 - $313.93
Q1 2021	17,900	$2,094	$116.59	$105.16 - $131.99
Q4 2020	17,900	$1,990	$122.23	$107.55 - $137.28
Q3 2020	18,300	$2,173	$108.57	$98.65 - $125.06
Q2 2020	17,700	$2,005	$98.34	$56.82 - $127.25
Q1 2020	16,300	$1,088	$83.31	$60.86 - $94.74
Q4 2019	16,500	$1,503	$96.98	$82.31 - $121.21
Q3 2019	14,000	$1,207	$93.82	$82.39 - $108.37
Q2 2019	6,238	$654	$107.12	$89.83 - $145.16
Q1 2019	5,438	$681	$124.30	$102.43 - $148.18
Q4 2018	5,538	$624	$154.76	$91.56 - $222.29
Q3 2018	10,718	$2,295	$250.94	$193.57 - $315.00
Q2 2018	5,908	$1,652	$175.60	$98.81 - $325.98
Q1 2018	3,868	$452	$123.44	$90.56 - $154.75