MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

SCHRODER INVESTMENT MANAGEMENT GROUP's Holding History (CIK: 0001086619)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 29,051 Value ($000) $16,958 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 16,612 Value ($000) $7,361 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 33,207 Value ($000) $10,050 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 30,406 Value ($000) $9,969 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 11,047 Value ($000) $3,442 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 20,842 Value ($000) $4,427 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 12,708 Value ($000) $3,560 Avg Close $238.04 Range $189.00 - $295.50

Q1 2024

Shares 23,701 Value ($000) $6,329 Avg Close $235.62 Range $168.25 - $299.98

Q4 2023

Shares 18,300 Value ($000) $4,234 Avg Close $174.99 Range $119.76 - $245.31

Q4 2019

Shares 981 Value ($000) $89 Avg Close $96.98 Range $82.31 - $121.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	29,051	$16,958	$510.76	$393.61 - $615.00
Q3 2025	16,612	$7,361	$373.08	$284.02 - $460.22
Q2 2025	33,207	$10,050	$297.95	$265.00 - $349.00
Q1 2025	30,406	$9,969	$328.59	$266.44 - $377.46
Q4 2024	11,047	$3,442	$281.26	$200.63 - $368.29
Q3 2024	20,842	$4,427	$255.83	$208.94 - $298.00
Q2 2024	12,708	$3,560	$238.04	$189.00 - $295.50
Q1 2024	23,701	$6,329	$235.62	$168.25 - $299.98
Q4 2023	18,300	$4,234	$174.99	$119.76 - $245.31
Q4 2019	981	$89	$96.98	$82.31 - $121.21