MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

GEODE CAPITAL MANAGEMENT, LLC's Holding History (CIK: 0001214717)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 451,743 Value ($000) $263,114 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 446,233 Value ($000) $204,701 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 414,392 Value ($000) $125,428 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 420,875 Value ($000) $139,437 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 410,578 Value ($000) $126,719 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 405,655 Value ($000) $86,104 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 399,854 Value ($000) $112,045 Avg Close $238.04 Range $189.00 - $295.50

Q1 2024

Shares 346,857 Value ($000) $92,638 Avg Close $235.62 Range $168.25 - $299.98

Q4 2023

Shares 336,255 Value ($000) $77,812 Avg Close $174.99 Range $119.76 - $245.31

Q3 2023

Shares 296,438 Value ($000) $43,297 Avg Close $188.22 Range $143.75 - $239.76

Q2 2023

Shares 271,319 Value ($000) $62,675 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 248,057 Value ($000) $60,094 Avg Close $272.48 Range $222.87 - $313.93

Q4 2022

Shares 236,585 Value ($000) $69 Avg Close $97.80 Range $57.21 - $315.45

Q3 2022

Shares 229,786 Value ($000) $14,933 Avg Close $69.48 Range $59.47 - $82.00

Q2 2022

Shares 224,802 Value ($000) $16,091 Avg Close $73.50 Range $57.15 - $100.90

Q1 2022

Shares 217,988 Value ($000) $21,388 Avg Close $84.31 Range $52.33 - $105.93

Q4 2021

Shares 220,018 Value ($000) $18,644 Avg Close $82.16 Range $68.56 - $102.42

Q3 2021

Shares 202,375 Value ($000) $16,147 Avg Close $86.38 Range $77.60 - $105.72

Q2 2021

Shares 198,104 Value ($000) $19,297 Avg Close $118.38 Range $95.21 - $142.62

Q1 2021

Shares 154,796 Value ($000) $18,106 Avg Close $116.59 Range $105.16 - $131.99

Q4 2020

Shares 142,006 Value ($000) $15,786 Avg Close $122.23 Range $107.55 - $137.28

Q3 2020

Shares 138,026 Value ($000) $16,387 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 138,790 Value ($000) $15,717 Avg Close $98.34 Range $56.82 - $127.25

Q1 2020

Shares 138,920 Value ($000) $9,274 Avg Close $83.31 Range $60.86 - $94.74

Q4 2019

Shares 123,933 Value ($000) $11,291 Avg Close $96.98 Range $82.31 - $121.21

Q3 2019

Shares 111,901 Value ($000) $9,648 Avg Close $93.82 Range $82.39 - $108.37

Q2 2019

Shares 109,468 Value ($000) $11,473 Avg Close $107.12 Range $89.83 - $145.16

Q1 2019

Shares 99,573 Value ($000) $12,472 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 90,516 Value ($000) $10,202 Avg Close $154.76 Range $91.56 - $222.29

Q3 2018

Shares 85,980 Value ($000) $18,410 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 80,016 Value ($000) $22,379 Avg Close $175.60 Range $98.81 - $325.98

Q1 2018

Shares 51,502 Value ($000) $6,014 Avg Close $123.44 Range $90.56 - $154.75

Q4 2017

Shares 54,299 Value ($000) $4,984 Avg Close $57.12 Range $38.82 - $101.00

Q3 2017

Shares 35,980 Value ($000) $1,618 Avg Close $18.72 Range $15.15 - $49.48

Q2 2017

Shares 32,240 Value ($000) $524 Avg Close $15.63 Range $13.09 - $17.84

Q1 2017

Shares 25,821 Value ($000) $397 Avg Close $15.73 Range $14.78 - $16.63

Q4 2016

Shares 25,605 Value ($000) $381 Avg Close $16.07 Range $12.60 - $18.24

Q3 2016

Shares 18,317 Value ($000) $232 Avg Close $9.69 Range $6.60 - $14.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	451,743	$263,114	$510.76	$393.61 - $615.00
Q3 2025	446,233	$204,701	$373.08	$284.02 - $460.22
Q2 2025	414,392	$125,428	$297.95	$265.00 - $349.00
Q1 2025	420,875	$139,437	$328.59	$266.44 - $377.46
Q4 2024	410,578	$126,719	$281.26	$200.63 - $368.29
Q3 2024	405,655	$86,104	$255.83	$208.94 - $298.00
Q2 2024	399,854	$112,045	$238.04	$189.00 - $295.50
Q1 2024	346,857	$92,638	$235.62	$168.25 - $299.98
Q4 2023	336,255	$77,812	$174.99	$119.76 - $245.31
Q3 2023	296,438	$43,297	$188.22	$143.75 - $239.76
Q2 2023	271,319	$62,675	$270.85	$192.22 - $322.67
Q1 2023	248,057	$60,094	$272.48	$222.87 - $313.93
Q4 2022	236,585	$69	$97.80	$57.21 - $315.45
Q3 2022	229,786	$14,933	$69.48	$59.47 - $82.00
Q2 2022	224,802	$16,091	$73.50	$57.15 - $100.90
Q1 2022	217,988	$21,388	$84.31	$52.33 - $105.93
Q4 2021	220,018	$18,644	$82.16	$68.56 - $102.42
Q3 2021	202,375	$16,147	$86.38	$77.60 - $105.72
Q2 2021	198,104	$19,297	$118.38	$95.21 - $142.62
Q1 2021	154,796	$18,106	$116.59	$105.16 - $131.99
Q4 2020	142,006	$15,786	$122.23	$107.55 - $137.28
Q3 2020	138,026	$16,387	$108.57	$98.65 - $125.06
Q2 2020	138,790	$15,717	$98.34	$56.82 - $127.25
Q1 2020	138,920	$9,274	$83.31	$60.86 - $94.74
Q4 2019	123,933	$11,291	$96.98	$82.31 - $121.21
Q3 2019	111,901	$9,648	$93.82	$82.39 - $108.37
Q2 2019	109,468	$11,473	$107.12	$89.83 - $145.16
Q1 2019	99,573	$12,472	$124.30	$102.43 - $148.18
Q4 2018	90,516	$10,202	$154.76	$91.56 - $222.29
Q3 2018	85,980	$18,410	$250.94	$193.57 - $315.00
Q2 2018	80,016	$22,379	$175.60	$98.81 - $325.98
Q1 2018	51,502	$6,014	$123.44	$90.56 - $154.75
Q4 2017	54,299	$4,984	$57.12	$38.82 - $101.00
Q3 2017	35,980	$1,618	$18.72	$15.15 - $49.48
Q2 2017	32,240	$524	$15.63	$13.09 - $17.84
Q1 2017	25,821	$397	$15.73	$14.78 - $16.63
Q4 2016	25,605	$381	$16.07	$12.60 - $18.24
Q3 2016	18,317	$232	$9.69	$6.60 - $14.00