MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,978 Value ($000) $4,064 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 1,798 Value ($000) $825 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 10,835 Value ($000) $3,279 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 2,507 Value ($000) $830 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 1,314 Value ($000) $405 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 8,930 Value ($000) $1,895 Avg Close $255.83 Range $208.94 - $298.00

Q1 2024

Shares 5,653 Value ($000) $1,510 Avg Close $235.62 Range $168.25 - $299.98

Q3 2023

Shares 25,857 Value ($000) $3,776 Avg Close $188.22 Range $143.75 - $239.76

Q2 2023

Shares 28,010 Value ($000) $6,470 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 120,287 Value ($000) $29 Avg Close $272.48 Range $222.87 - $313.93

Q3 2022

Shares 11,738 Value ($000) $763 Avg Close $69.48 Range $59.47 - $82.00

Q2 2022

Shares 4,381 Value ($000) $314 Avg Close $73.50 Range $57.15 - $100.90

Q4 2021

Shares 15,782 Value ($000) $1,337 Avg Close $82.16 Range $68.56 - $102.42

Q3 2021

Shares 24,019 Value ($000) $1,916 Avg Close $86.38 Range $77.60 - $105.72

Q2 2021

Shares 45,883 Value ($000) $4,469 Avg Close $118.38 Range $95.21 - $142.62

Q1 2021

Shares 6,399 Value ($000) $748 Avg Close $116.59 Range $105.16 - $131.99

Q3 2020

Shares 4,434 Value ($000) $526 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 40,775 Value ($000) $4,618 Avg Close $98.34 Range $56.82 - $127.25

Q1 2020

Shares 50,747 Value ($000) $3,388 Avg Close $83.31 Range $60.86 - $94.74

Q3 2019

Shares 18,960 Value ($000) $1,634 Avg Close $93.82 Range $82.39 - $108.37

Q2 2019

Shares 12,231 Value ($000) $1,282 Avg Close $107.12 Range $89.83 - $145.16

Q1 2019

Shares 5,111 Value ($000) $640 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 25,278 Value ($000) $2,849 Avg Close $154.76 Range $91.56 - $222.29

Q2 2018

Shares 46,505 Value ($000) $13,007 Avg Close $175.60 Range $98.81 - $325.98

Q1 2018

Shares 92,291 Value ($000) $10,779 Avg Close $123.44 Range $90.56 - $154.75

Q4 2017

Shares 3,905 Value ($000) $358 Avg Close $57.12 Range $38.82 - $101.00

Q1 2017

Shares 31,571 Value ($000) $486 Avg Close $15.73 Range $14.78 - $16.63

Q3 2016

Shares 16,202 Value ($000) $205 Avg Close $9.69 Range $6.60 - $14.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,978	$4,064	$510.76	$393.61 - $615.00
Q3 2025	1,798	$825	$373.08	$284.02 - $460.22
Q2 2025	10,835	$3,279	$297.95	$265.00 - $349.00
Q1 2025	2,507	$830	$328.59	$266.44 - $377.46
Q4 2024	1,314	$405	$281.26	$200.63 - $368.29
Q3 2024	8,930	$1,895	$255.83	$208.94 - $298.00
Q1 2024	5,653	$1,510	$235.62	$168.25 - $299.98
Q3 2023	25,857	$3,776	$188.22	$143.75 - $239.76
Q2 2023	28,010	$6,470	$270.85	$192.22 - $322.67
Q1 2023	120,287	$29	$272.48	$222.87 - $313.93
Q3 2022	11,738	$763	$69.48	$59.47 - $82.00
Q2 2022	4,381	$314	$73.50	$57.15 - $100.90
Q4 2021	15,782	$1,337	$82.16	$68.56 - $102.42
Q3 2021	24,019	$1,916	$86.38	$77.60 - $105.72
Q2 2021	45,883	$4,469	$118.38	$95.21 - $142.62
Q1 2021	6,399	$748	$116.59	$105.16 - $131.99
Q3 2020	4,434	$526	$108.57	$98.65 - $125.06
Q2 2020	40,775	$4,618	$98.34	$56.82 - $127.25
Q1 2020	50,747	$3,388	$83.31	$60.86 - $94.74
Q3 2019	18,960	$1,634	$93.82	$82.39 - $108.37
Q2 2019	12,231	$1,282	$107.12	$89.83 - $145.16
Q1 2019	5,111	$640	$124.30	$102.43 - $148.18
Q4 2018	25,278	$2,849	$154.76	$91.56 - $222.29
Q2 2018	46,505	$13,007	$175.60	$98.81 - $325.98
Q1 2018	92,291	$10,779	$123.44	$90.56 - $154.75
Q4 2017	3,905	$358	$57.12	$38.82 - $101.00
Q1 2017	31,571	$486	$15.73	$14.78 - $16.63
Q3 2016	16,202	$205	$9.69	$6.60 - $14.00