MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 46,120 Value ($000) $26,858 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 9,000 Value ($000) $4,128 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 5,400 Value ($000) $1,634 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 1,100 Value ($000) $364 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 13,400 Value ($000) $4,135 Avg Close $281.26 Range $200.63 - $368.29

Q2 2023

Shares 6,100 Value ($000) $1,409 Avg Close $270.85 Range $192.22 - $322.67

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	46,120	$26,858	$510.76	$393.61 - $615.00
Q3 2025	9,000	$4,128	$373.08	$284.02 - $460.22
Q2 2025	5,400	$1,634	$297.95	$265.00 - $349.00
Q1 2025	1,100	$364	$328.59	$266.44 - $377.46
Q4 2024	13,400	$4,135	$281.26	$200.63 - $368.29
Q2 2023	6,100	$1,409	$270.85	$192.22 - $322.67