MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018

Shares 33,000 Value ($000) $7,066 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 46,000 Value ($000) $12,866 Avg Close $175.60 Range $98.81 - $325.98

Q1 2018

Shares 25,000 Value ($000) $2,920 Avg Close $123.44 Range $90.56 - $154.75

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2018	33,000	$7,066	$250.94	$193.57 - $315.00
Q2 2018	46,000	$12,866	$175.60	$98.81 - $325.98
Q1 2018	25,000	$2,920	$123.44	$90.56 - $154.75