MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

ArrowMark Colorado Holdings LLC's Holding History (CIK: 0001483859)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 82,624 Value ($000) $48,115 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 123,259 Value ($000) $56,534 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 144,808 Value ($000) $43,825 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 180,109 Value ($000) $59,658 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 199,667 Value ($000) $61,611 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 161,952 Value ($000) $34,369 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 187,393 Value ($000) $52,500 Avg Close $238.04 Range $189.00 - $295.50

Q1 2024

Shares 34,219 Value ($000) $9,138 Avg Close $235.62 Range $168.25 - $299.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	82,624	$48,115	$510.76	$393.61 - $615.00
Q3 2025	123,259	$56,534	$373.08	$284.02 - $460.22
Q2 2025	144,808	$43,825	$297.95	$265.00 - $349.00
Q1 2025	180,109	$59,658	$328.59	$266.44 - $377.46
Q4 2024	199,667	$61,611	$281.26	$200.63 - $368.29
Q3 2024	161,952	$34,369	$255.83	$208.94 - $298.00
Q2 2024	187,393	$52,500	$238.04	$189.00 - $295.50
Q1 2024	34,219	$9,138	$235.62	$168.25 - $299.98