MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 93,114 Value ($000) $54,224 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 95,734 Value ($000) $43,909 Avg Close $373.08 Range $284.02 - $460.22

Q1 2025

Shares 51,890 Value ($000) $17,188 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 7,819 Value ($000) $2,413 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 14,897 Value ($000) $3,161 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 36,204 Value ($000) $10,143 Avg Close $238.04 Range $189.00 - $295.50

Q1 2024

Shares 25,151 Value ($000) $6,716 Avg Close $235.62 Range $168.25 - $299.98

Q4 2023

Shares 216,818 Value ($000) $50,167 Avg Close $174.99 Range $119.76 - $245.31

Q3 2023

Shares 103,386 Value ($000) $15,098 Avg Close $188.22 Range $143.75 - $239.76

Q2 2023

Shares 40,223 Value ($000) $9,292 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 115,192 Value ($000) $27,906 Avg Close $272.48 Range $222.87 - $313.93

Q4 2022

Shares 44,080 Value ($000) $12,794 Avg Close $97.80 Range $57.21 - $315.45

Q2 2022

Shares 27,392 Value ($000) $1,960 Avg Close $73.50 Range $57.15 - $100.90

Q1 2022

Shares 26,895 Value ($000) $2,639 Avg Close $84.31 Range $52.33 - $105.93

Q4 2021

Shares 36,040 Value ($000) $3,054 Avg Close $82.16 Range $68.56 - $102.42

Q2 2021

Shares 11,427 Value ($000) $1,113 Avg Close $118.38 Range $95.21 - $142.62

Q1 2021

Shares 11,308 Value ($000) $1,323 Avg Close $116.59 Range $105.16 - $131.99

Q4 2020

Shares 8,025 Value ($000) $892 Avg Close $122.23 Range $107.55 - $137.28

Q3 2020

Shares 9,863 Value ($000) $1,171 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 47,243 Value ($000) $5,350 Avg Close $98.34 Range $56.82 - $127.25

Q3 2019

Shares 3,697 Value ($000) $319 Avg Close $93.82 Range $82.39 - $108.37

Q2 2019

Shares 2,523 Value ($000) $265 Avg Close $107.12 Range $89.83 - $145.16

Q1 2019

Shares 2,340 Value ($000) $293 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 1,993 Value ($000) $225 Avg Close $154.76 Range $91.56 - $222.29

Q3 2018

Shares 2,491 Value ($000) $533 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 1,852 Value ($000) $518 Avg Close $175.60 Range $98.81 - $325.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	93,114	$54,224	$510.76	$393.61 - $615.00
Q3 2025	95,734	$43,909	$373.08	$284.02 - $460.22
Q1 2025	51,890	$17,188	$328.59	$266.44 - $377.46
Q4 2024	7,819	$2,413	$281.26	$200.63 - $368.29
Q3 2024	14,897	$3,161	$255.83	$208.94 - $298.00
Q2 2024	36,204	$10,143	$238.04	$189.00 - $295.50
Q1 2024	25,151	$6,716	$235.62	$168.25 - $299.98
Q4 2023	216,818	$50,167	$174.99	$119.76 - $245.31
Q3 2023	103,386	$15,098	$188.22	$143.75 - $239.76
Q2 2023	40,223	$9,292	$270.85	$192.22 - $322.67
Q1 2023	115,192	$27,906	$272.48	$222.87 - $313.93
Q4 2022	44,080	$12,794	$97.80	$57.21 - $315.45
Q2 2022	27,392	$1,960	$73.50	$57.15 - $100.90
Q1 2022	26,895	$2,639	$84.31	$52.33 - $105.93
Q4 2021	36,040	$3,054	$82.16	$68.56 - $102.42
Q2 2021	11,427	$1,113	$118.38	$95.21 - $142.62
Q1 2021	11,308	$1,323	$116.59	$105.16 - $131.99
Q4 2020	8,025	$892	$122.23	$107.55 - $137.28
Q3 2020	9,863	$1,171	$108.57	$98.65 - $125.06
Q2 2020	47,243	$5,350	$98.34	$56.82 - $127.25
Q3 2019	3,697	$319	$93.82	$82.39 - $108.37
Q2 2019	2,523	$265	$107.12	$89.83 - $145.16
Q1 2019	2,340	$293	$124.30	$102.43 - $148.18
Q4 2018	1,993	$225	$154.76	$91.56 - $222.29
Q3 2018	2,491	$533	$250.94	$193.57 - $315.00
Q2 2018	1,852	$518	$175.60	$98.81 - $325.98