MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC's Holding History (CIK: 0001644956)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 354,220 Value ($000) $206,276 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 411,802 Value ($000) $188,877 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 350,289 Value ($000) $106,011 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 353,155 Value ($000) $116,976 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 371,771 Value ($000) $114,717 Avg Close $281.26 Range $200.63 - $368.29

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	354,220	$206,276	$510.76	$393.61 - $615.00
Q3 2025	411,802	$188,877	$373.08	$284.02 - $460.22
Q2 2025	350,289	$106,011	$297.95	$265.00 - $349.00
Q1 2025	353,155	$116,976	$328.59	$266.44 - $377.46
Q4 2024	371,771	$114,717	$281.26	$200.63 - $368.29