MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

Aigen Investment Management, LP's Holding History (CIK: 0001741224)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,652 Value ($000) $1,544 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 585 Value ($000) $268 Avg Close $373.08 Range $284.02 - $460.22

Q4 2024

Shares 1,771 Value ($000) $546 Avg Close $281.26 Range $200.63 - $368.29

Q2 2023

Shares 2,270 Value ($000) $524 Avg Close $270.85 Range $192.22 - $322.67

Q1 2023

Shares 3,132 Value ($000) $759 Avg Close $272.48 Range $222.87 - $313.93

Q3 2020

Shares 1,759 Value ($000) $209 Avg Close $108.57 Range $98.65 - $125.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,652	$1,544	$510.76	$393.61 - $615.00
Q3 2025	585	$268	$373.08	$284.02 - $460.22
Q4 2024	1,771	$546	$281.26	$200.63 - $368.29
Q2 2023	2,270	$524	$270.85	$192.22 - $322.67
Q1 2023	3,132	$759	$272.48	$222.87 - $313.93
Q3 2020	1,759	$209	$108.57	$98.65 - $125.06