MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

Vanguard Personalized Indexing Management, LLC's Holding History (CIK: 0001767306)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,249 Value ($000) $727 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 1,089 Value ($000) $499 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 984 Value ($000) $298 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 963 Value ($000) $319 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 790 Value ($000) $244 Avg Close $281.26 Range $200.63 - $368.29

Q2 2024

Shares 728 Value ($000) $204 Avg Close $238.04 Range $189.00 - $295.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,249	$727	$510.76	$393.61 - $615.00
Q3 2025	1,089	$499	$373.08	$284.02 - $460.22
Q2 2025	984	$298	$297.95	$265.00 - $349.00
Q1 2025	963	$319	$328.59	$266.44 - $377.46
Q4 2024	790	$244	$281.26	$200.63 - $368.29
Q2 2024	728	$204	$238.04	$189.00 - $295.50