MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

J. Safra Sarasin Holding AG's Holding History (CIK: 0001890222)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,546 Value ($000) $900 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 2,397 Value ($000) $1,099 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 6,823 Value ($000) $2,065 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 1,792 Value ($000) $594 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 3,405 Value ($000) $1,051 Avg Close $281.26 Range $200.63 - $368.29

Q3 2024

Shares 5,600 Value ($000) $1,188 Avg Close $255.83 Range $208.94 - $298.00

Q2 2024

Shares 5,751 Value ($000) $1,611 Avg Close $238.04 Range $189.00 - $295.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,546	$900	$510.76	$393.61 - $615.00
Q3 2025	2,397	$1,099	$373.08	$284.02 - $460.22
Q2 2025	6,823	$2,065	$297.95	$265.00 - $349.00
Q1 2025	1,792	$594	$328.59	$266.44 - $377.46
Q4 2024	3,405	$1,051	$281.26	$200.63 - $368.29
Q3 2024	5,600	$1,188	$255.83	$208.94 - $298.00
Q2 2024	5,751	$1,611	$238.04	$189.00 - $295.50