MAST THERAPEUTICS INC

CUSIP: 576314108 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 1,000,262 Value ($000) $124 Avg Close — Range —
Q4 2016
Shares 1,448,762 Value ($000) $126 Avg Close — Range —
Q3 2016
Shares 1,396,562 Value ($000) $154 Avg Close — Range —
Q2 2016
Shares 831,162 Value ($000) $391 Avg Close — Range —
Q1 2016
Shares 21,470 Value ($000) $6 Avg Close — Range —
Q2 2015
Shares 393,055 Value ($000) $193 Avg Close — Range —
Q1 2015
Shares 602,094 Value ($000) $292 Avg Close — Range —
Q4 2014
Shares 242,475 Value ($000) $136 Avg Close — Range —
Q4 2013
Shares 1,535,000 Value ($000) $710 Avg Close — Range —
Q3 2013
Shares 365,500 Value ($000) $160 Avg Close — Range —