MASTERCARD INCORPORATED

Ticker: MA CUSIP: 57636Q104 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 12,100 Value ($000) $4,324 Avg Close $351.61 Range $298.93 - $391.17

Q3 2018

Shares 22,760 Value ($000) $5,067 Avg Close $200.34 Range $186.80 - $215.48

Q2 2018

Shares 22,760 Value ($000) $4,473 Avg Close $180.31 Range $160.86 - $195.68

Q1 2018

Shares 16,525 Value ($000) $2,895 Avg Close $163.70 Range $144.52 - $175.98

Q4 2017

Shares 11,525 Value ($000) $1,744 Avg Close $142.19 Range $134.47 - $147.90

Q3 2017

Shares 11,525 Value ($000) $1,627 Avg Close $126.35 Range $115.06 - $137.11

Q2 2017

Shares 11,525 Value ($000) $1,400 Avg Close $113.06 Range $105.80 - $120.27

Q1 2017

Shares 11,525 Value ($000) $1,296 Avg Close $104.26 Range $98.83 - $107.97

Q4 2016

Shares 10,825 Value ($000) $1,118 Avg Close $98.27 Range $94.46 - $103.40

Q4 2015

Shares 30,605 Value ($000) $2,980 Avg Close $92.19 Range $83.59 - $95.82

Q3 2014

Shares 26,000 Value ($000) $1,922 Avg Close $71.09 Range $68.75 - $73.96

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	12,100	$4,324	$351.61	$298.93 - $391.17
Q3 2018	22,760	$5,067	$200.34	$186.80 - $215.48
Q2 2018	22,760	$4,473	$180.31	$160.86 - $195.68
Q1 2018	16,525	$2,895	$163.70	$144.52 - $175.98
Q4 2017	11,525	$1,744	$142.19	$134.47 - $147.90
Q3 2017	11,525	$1,627	$126.35	$115.06 - $137.11
Q2 2017	11,525	$1,400	$113.06	$105.80 - $120.27
Q1 2017	11,525	$1,296	$104.26	$98.83 - $107.97
Q4 2016	10,825	$1,118	$98.27	$94.46 - $103.40
Q4 2015	30,605	$2,980	$92.19	$83.59 - $95.82
Q3 2014	26,000	$1,922	$71.09	$68.75 - $73.96