MAZE THERAPEUTICS INC

Ticker: MAZE CUSIP: 578784100 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,245 Value ($000) $300 Avg Close $34.37 Range $24.99 - $43.29

Q3 2025

Shares 11,150 Value ($000) $289 Avg Close $16.88 Range $10.98 - $28.37

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,245	$300	$34.37	$24.99 - $43.29
Q3 2025	11,150	$289	$16.88	$10.98 - $28.37