MONOPAR THERAPEUTICS INC

Ticker: MNPR CUSIP: 61023L207 Class: Common Stock

JANUS HENDERSON GROUP PLC's Holding History (CIK: 0001274173)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,317,410 Value ($000) $85,908 Avg Close $81.71 Range $63.73 - $105.00

Q3 2025

Shares 1,287,368 Value ($000) $105,313 Avg Close $44.70 Range $29.18 - $81.89

Q2 2025

Shares 1,172,368 Value ($000) $41,596 Avg Close $36.32 Range $26.05 - $46.60

Q1 2025

Shares 1,134,406 Value ($000) $45,597 Avg Close $36.03 Range $21.00 - $54.30

Q4 2024

Shares 1,046,899 Value ($000) $23,435 Avg Close $16.78 Range $4.50 - $38.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,317,410	$85,908	$81.71	$63.73 - $105.00
Q3 2025	1,287,368	$105,313	$44.70	$29.18 - $81.89
Q2 2025	1,172,368	$41,596	$36.32	$26.05 - $46.60
Q1 2025	1,134,406	$45,597	$36.03	$21.00 - $54.30
Q4 2024	1,046,899	$23,435	$16.78	$4.50 - $38.50