MONOPAR THERAPEUTICS INC

Ticker: MNPR CUSIP: 61023L207 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 667,207 Value ($000) $43,569 Avg Close $81.71 Range $63.73 - $105.00

Q3 2025

Shares 511,207 Value ($000) $41,750 Avg Close $44.70 Range $29.18 - $81.89

Q2 2025

Shares 511,207 Value ($000) $18,291 Avg Close $36.32 Range $26.05 - $46.60

Q1 2025

Shares 511,207 Value ($000) $18,613 Avg Close $36.03 Range $21.00 - $54.30

Q4 2024

Shares 511,207 Value ($000) $11,247 Avg Close $16.78 Range $4.50 - $38.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	667,207	$43,569	$81.71	$63.73 - $105.00
Q3 2025	511,207	$41,750	$44.70	$29.18 - $81.89
Q2 2025	511,207	$18,291	$36.32	$26.05 - $46.60
Q1 2025	511,207	$18,613	$36.03	$21.00 - $54.30
Q4 2024	511,207	$11,247	$16.78	$4.50 - $38.50