NANOSPHERE INC

CUSIP: 63009F105 Class: COM

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 14,000 Value ($000) $3 Avg Close — Range —
Q4 2014
Shares 16,500 Value ($000) $6 Avg Close — Range —
Q3 2014
Shares 16,500 Value ($000) $10 Avg Close — Range —
Q2 2014
Shares 15,500 Value ($000) $24 Avg Close — Range —
Q1 2014
Shares 15,500 Value ($000) $34 Avg Close — Range —
Q4 2013
Shares 12,500 Value ($000) $28 Avg Close — Range —
Q3 2013
Shares 7,000 Value ($000) $14 Avg Close — Range —
Q2 2013
Shares 3,000 Value ($000) $9 Avg Close — Range —