NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 442,866 Value ($000) $62,812 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 977,210 Value ($000) $137,181 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 1,194,219 Value ($000) $150,101 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 576,590 Value ($000) $63,771 Avg Close $126.68 Range $105.18 - $154.61

Q4 2024

Shares 418,712 Value ($000) $57,154 Avg Close $123.68 Range $110.95 - $140.00

Q3 2024

Shares 312,767 Value ($000) $36,037 Avg Close $137.09 Range $114.08 - $157.98

Q2 2024

Shares 187,483 Value ($000) $25,811 Avg Close $137.14 Range $129.33 - $145.78

Q1 2024

Shares 455,220 Value ($000) $62,784 Avg Close $136.57 Range $128.00 - $148.37

Q4 2023

Shares 688,956 Value ($000) $90,777 Avg Close $115.11 Range $103.63 - $133.64

Q3 2023

Shares 1,268,266 Value ($000) $142,680 Avg Close $105.30 Range $93.28 - $119.29

Q2 2023

Shares 850,258 Value ($000) $80,179 Avg Close $97.71 Range $89.04 - $107.98

Q1 2023

Shares 568,275 Value ($000) $58 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 840,340 Value ($000) $100 Avg Close $117.13 Range $105.14 - $129.29

Q3 2022

Shares 573,056 Value ($000) $60,864 Avg Close $101.46 Range $91.53 - $109.26

Q2 2022

Shares 362,673 Value ($000) $35,353 Avg Close $92.29 Range $75.25 - $100.73

Q1 2022

Shares 500,127 Value ($000) $46,887 Avg Close $84.75 Range $71.88 - $95.87

Q4 2021

Shares 560,997 Value ($000) $47,780 Avg Close $91.99 Range $78.31 - $108.02

Q3 2021

Shares 491,244 Value ($000) $47,115 Avg Close $94.46 Range $84.77 - $101.43

Q2 2021

Shares 121,511 Value ($000) $11,825 Avg Close $95.85 Range $87.19 - $103.72

Q4 2020

Shares 225,156 Value ($000) $21,581 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 42,636 Value ($000) $4,100 Avg Close $115.68 Range $95.42 - $136.26

Q2 2020

Shares 59,150 Value ($000) $7,216 Avg Close $110.51 Range $82.51 - $131.00

Q1 2020

Shares 116,800 Value ($000) $10,109 Avg Close $97.87 Range $72.14 - $115.24

Q4 2019

Shares 386,058 Value ($000) $41,497 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 277,052 Value ($000) $24,965 Avg Close $93.43 Range $83.19 - $102.51

Q2 2019

Shares 203,710 Value ($000) $17,199 Avg Close $82.11 Range $71.85 - $91.98

Q1 2019

Shares 559,948 Value ($000) $49,331 Avg Close $83.58 Range $67.10 - $92.71

Q4 2018

Shares 20,740 Value ($000) $1,481 Avg Close $95.81 Range $64.72 - $125.59

Q3 2018

Shares 358,535 Value ($000) $44,082 Avg Close $113.46 Range $96.98 - $126.98

Q2 2018

Shares 27,189 Value ($000) $2,671 Avg Close $89.51 Range $74.34 - $106.26

Q1 2018

Shares 127,915 Value ($000) $10,608 Avg Close $84.45 Range $74.12 - $92.98

Q4 2017

Shares 534,566 Value ($000) $41,477 Avg Close $68.21 Range $57.71 - $78.05

Q3 2017

Shares 116,905 Value ($000) $7,164 Avg Close $52.77 Range $44.75 - $61.51

Q4 2016

Shares 1,335,798 Value ($000) $51,695 Avg Close $45.27 Range $37.35 - $54.91

Q3 2016

Shares 107,968 Value ($000) $5,467 Avg Close $49.80 Range $44.69 - $55.15

Q2 2016

Shares 614,576 Value ($000) $27,932 Avg Close $46.04 Range $39.01 - $53.00

Q1 2016

Shares 1,088,915 Value ($000) $43,067 Avg Close $39.68 Range $31.25 - $55.94

Q4 2015

Shares 1,057,623 Value ($000) $59,830 Avg Close $50.83 Range $37.76 - $58.46

Q3 2015

Shares 1,325,374 Value ($000) $52,737 Avg Close $48.33 Range $33.61 - $56.97

Q2 2015

Shares 1,156,887 Value ($000) $55,253 Avg Close $42.40 Range $32.67 - $49.49

Q1 2015

Shares 1,472,873 Value ($000) $58,488 Avg Close $35.77 Range $19.68 - $45.36

Q4 2014

Shares 1,221,666 Value ($000) $27,292 Avg Close $18.95 Range $15.20 - $24.86

Q3 2014

Shares 341,926 Value ($000) $5,358 Avg Close $14.95 Range $12.63 - $17.00

Q2 2014

Shares 408,941 Value ($000) $6,067 Avg Close $14.11 Range $12.17 - $16.47

Q4 2013

Shares 830,874 Value ($000) $7,760 Avg Close $9.76 Range $8.57 - $11.88

Q3 2013

Shares 65,000 Value ($000) $736 Avg Close $13.75 Range $10.42 - $16.74

Q2 2013

Shares 80,819 Value ($000) $1,081 Avg Close $12.28 Range $10.87 - $14.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	442,866	$62,812	$144.87	$133.61 - $160.18
Q3 2025	977,210	$137,181	$135.50	$123.67 - $148.00
Q2 2025	1,194,219	$150,101	$114.68	$84.23 - $130.46
Q1 2025	576,590	$63,771	$126.68	$105.18 - $154.61
Q4 2024	418,712	$57,154	$123.68	$110.95 - $140.00
Q3 2024	312,767	$36,037	$137.09	$114.08 - $157.98
Q2 2024	187,483	$25,811	$137.14	$129.33 - $145.78
Q1 2024	455,220	$62,784	$136.57	$128.00 - $148.37
Q4 2023	688,956	$90,777	$115.11	$103.63 - $133.64
Q3 2023	1,268,266	$142,680	$105.30	$93.28 - $119.29
Q2 2023	850,258	$80,179	$97.71	$89.04 - $107.98
Q1 2023	568,275	$58	$104.06	$92.89 - $125.02
Q4 2022	840,340	$100	$117.13	$105.14 - $129.29
Q3 2022	573,056	$60,864	$101.46	$91.53 - $109.26
Q2 2022	362,673	$35,353	$92.29	$75.25 - $100.73
Q1 2022	500,127	$46,887	$84.75	$71.88 - $95.87
Q4 2021	560,997	$47,780	$91.99	$78.31 - $108.02
Q3 2021	491,244	$47,115	$94.46	$84.77 - $101.43
Q2 2021	121,511	$11,825	$95.85	$87.19 - $103.72
Q4 2020	225,156	$21,581	$96.59	$86.02 - $108.93
Q3 2020	42,636	$4,100	$115.68	$95.42 - $136.26
Q2 2020	59,150	$7,216	$110.51	$82.51 - $131.00
Q1 2020	116,800	$10,109	$97.87	$72.14 - $115.24
Q4 2019	386,058	$41,497	$104.70	$84.68 - $119.65
Q3 2019	277,052	$24,965	$93.43	$83.19 - $102.51
Q2 2019	203,710	$17,199	$82.11	$71.85 - $91.98
Q1 2019	559,948	$49,331	$83.58	$67.10 - $92.71
Q4 2018	20,740	$1,481	$95.81	$64.72 - $125.59
Q3 2018	358,535	$44,082	$113.46	$96.98 - $126.98
Q2 2018	27,189	$2,671	$89.51	$74.34 - $106.26
Q1 2018	127,915	$10,608	$84.45	$74.12 - $92.98
Q4 2017	534,566	$41,477	$68.21	$57.71 - $78.05
Q3 2017	116,905	$7,164	$52.77	$44.75 - $61.51
Q4 2016	1,335,798	$51,695	$45.27	$37.35 - $54.91
Q3 2016	107,968	$5,467	$49.80	$44.69 - $55.15
Q2 2016	614,576	$27,932	$46.04	$39.01 - $53.00
Q1 2016	1,088,915	$43,067	$39.68	$31.25 - $55.94
Q4 2015	1,057,623	$59,830	$50.83	$37.76 - $58.46
Q3 2015	1,325,374	$52,737	$48.33	$33.61 - $56.97
Q2 2015	1,156,887	$55,253	$42.40	$32.67 - $49.49
Q1 2015	1,472,873	$58,488	$35.77	$19.68 - $45.36
Q4 2014	1,221,666	$27,292	$18.95	$15.20 - $24.86
Q3 2014	341,926	$5,358	$14.95	$12.63 - $17.00
Q2 2014	408,941	$6,067	$14.11	$12.17 - $16.47
Q4 2013	830,874	$7,760	$9.76	$8.57 - $11.88
Q3 2013	65,000	$736	$13.75	$10.42 - $16.74
Q2 2013	80,819	$1,081	$12.28	$10.87 - $14.06