NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

Palo Alto Investors LP's Holding History (CIK: 0001306923)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 18,117 Value ($000) $2,570 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 18,117 Value ($000) $2,543 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 13,334 Value ($000) $1,676 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 13,334 Value ($000) $1,475 Avg Close $126.68 Range $105.18 - $154.61

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	18,117	$2,570	$144.87	$133.61 - $160.18
Q3 2025	18,117	$2,543	$135.50	$123.67 - $148.00
Q2 2025	13,334	$1,676	$114.68	$84.23 - $130.46
Q1 2025	13,334	$1,475	$126.68	$105.18 - $154.61