NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 348,843 Value ($000) $49,476 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 97,289 Value ($000) $13,657 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 41,649 Value ($000) $5,235 Avg Close $114.68 Range $84.23 - $130.46

Q4 2024

Shares 2,425 Value ($000) $331 Avg Close $123.68 Range $110.95 - $140.00

Q1 2024

Shares 32,976 Value ($000) $4,548 Avg Close $136.57 Range $128.00 - $148.37

Q1 2023

Shares 162,683 Value ($000) $16,467 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 30,446 Value ($000) $3,636 Avg Close $117.13 Range $105.14 - $129.29

Q4 2021

Shares 10,553 Value ($000) $898 Avg Close $91.99 Range $78.31 - $108.02

Q4 2020

Shares 79,044 Value ($000) $7,576 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 146,943 Value ($000) $14,130 Avg Close $115.68 Range $95.42 - $136.26

Q4 2019

Shares 4,395 Value ($000) $473 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 66,566 Value ($000) $5,998 Avg Close $93.43 Range $83.19 - $102.51

Q1 2019

Shares 375,076 Value ($000) $33,044 Avg Close $83.58 Range $67.10 - $92.71

Q4 2018

Shares 707,475 Value ($000) $50,521 Avg Close $95.81 Range $64.72 - $125.59

Q3 2018

Shares 80,480 Value ($000) $9,895 Avg Close $113.46 Range $96.98 - $126.98

Q1 2018

Shares 8,144 Value ($000) $675 Avg Close $84.45 Range $74.12 - $92.98

Q2 2017

Shares 10,093 Value ($000) $464 Avg Close $48.51 Range $39.21 - $55.38

Q1 2017

Shares 24,628 Value ($000) $1,059 Avg Close $42.84 Range $38.38 - $47.43

Q4 2016

Shares 351,582 Value ($000) $13,607 Avg Close $45.27 Range $37.35 - $54.91

Q3 2016

Shares 209,689 Value ($000) $10,619 Avg Close $49.80 Range $44.69 - $55.15

Q2 2016

Shares 231,125 Value ($000) $10,505 Avg Close $46.04 Range $39.01 - $53.00

Q3 2014

Shares 51,860 Value ($000) $813 Avg Close $14.95 Range $12.63 - $17.00

Q2 2014

Shares 116,364 Value ($000) $1,727 Avg Close $14.11 Range $12.17 - $16.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	348,843	$49,476	$144.87	$133.61 - $160.18
Q3 2025	97,289	$13,657	$135.50	$123.67 - $148.00
Q2 2025	41,649	$5,235	$114.68	$84.23 - $130.46
Q4 2024	2,425	$331	$123.68	$110.95 - $140.00
Q1 2024	32,976	$4,548	$136.57	$128.00 - $148.37
Q1 2023	162,683	$16,467	$104.06	$92.89 - $125.02
Q4 2022	30,446	$3,636	$117.13	$105.14 - $129.29
Q4 2021	10,553	$898	$91.99	$78.31 - $108.02
Q4 2020	79,044	$7,576	$96.59	$86.02 - $108.93
Q3 2020	146,943	$14,130	$115.68	$95.42 - $136.26
Q4 2019	4,395	$473	$104.70	$84.68 - $119.65
Q3 2019	66,566	$5,998	$93.43	$83.19 - $102.51
Q1 2019	375,076	$33,044	$83.58	$67.10 - $92.71
Q4 2018	707,475	$50,521	$95.81	$64.72 - $125.59
Q3 2018	80,480	$9,895	$113.46	$96.98 - $126.98
Q1 2018	8,144	$675	$84.45	$74.12 - $92.98
Q2 2017	10,093	$464	$48.51	$39.21 - $55.38
Q1 2017	24,628	$1,059	$42.84	$38.38 - $47.43
Q4 2016	351,582	$13,607	$45.27	$37.35 - $54.91
Q3 2016	209,689	$10,619	$49.80	$44.69 - $55.15
Q2 2016	231,125	$10,505	$46.04	$39.01 - $53.00
Q3 2014	51,860	$813	$14.95	$12.63 - $17.00
Q2 2014	116,364	$1,727	$14.11	$12.17 - $16.47