NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 271,800 Value ($000) $38,549 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 285,300 Value ($000) $40,050 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 299,400 Value ($000) $37,632 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 285,500 Value ($000) $31,576 Avg Close $126.68 Range $105.18 - $154.61

Q4 2024

Shares 285,300 Value ($000) $38,943 Avg Close $123.68 Range $110.95 - $140.00

Q3 2024

Shares 298,700 Value ($000) $34,416 Avg Close $137.09 Range $114.08 - $157.98

Q2 2024

Shares 294,600 Value ($000) $40,558 Avg Close $137.14 Range $129.33 - $145.78

Q1 2024

Shares 294,200 Value ($000) $40,576 Avg Close $136.57 Range $128.00 - $148.37

Q4 2023

Shares 305,300 Value ($000) $40,226 Avg Close $115.11 Range $103.63 - $133.64

Q3 2023

Shares 313,800 Value ($000) $35,303 Avg Close $105.30 Range $93.28 - $119.29

Q2 2023

Shares 352,200 Value ($000) $33,212 Avg Close $97.71 Range $89.04 - $107.98

Q1 2023

Shares 380,500 Value ($000) $38,514 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 388,700 Value ($000) $46,426 Avg Close $117.13 Range $105.14 - $129.29

Q3 2022

Shares 414,227 Value ($000) $43,995 Avg Close $101.46 Range $91.53 - $109.26

Q2 2022

Shares 412,927 Value ($000) $40,252 Avg Close $92.29 Range $75.25 - $100.73

Q1 2022

Shares 410,827 Value ($000) $38,515 Avg Close $84.75 Range $71.88 - $95.87

Q4 2021

Shares 359,627 Value ($000) $30,629 Avg Close $91.99 Range $78.31 - $108.02

Q3 2021

Shares 372,927 Value ($000) $35,767 Avg Close $94.46 Range $84.77 - $101.43

Q2 2021

Shares 383,027 Value ($000) $37,276 Avg Close $95.85 Range $87.19 - $103.72

Q1 2021

Shares 340,700 Value ($000) $33,133 Avg Close $104.86 Range $87.37 - $120.27

Q4 2020

Shares 334,600 Value ($000) $32,071 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 343,400 Value ($000) $33,021 Avg Close $115.68 Range $95.42 - $136.26

Q2 2020

Shares 346,800 Value ($000) $42,310 Avg Close $110.51 Range $82.51 - $131.00

Q1 2020

Shares 339,500 Value ($000) $29,384 Avg Close $97.87 Range $72.14 - $115.24

Q4 2019

Shares 274,300 Value ($000) $29,485 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 171,800 Value ($000) $15,481 Avg Close $93.43 Range $83.19 - $102.51

Q2 2019

Shares 168,900 Value ($000) $14,260 Avg Close $82.11 Range $71.85 - $91.98

Q1 2019

Shares 165,200 Value ($000) $14,554 Avg Close $83.58 Range $67.10 - $92.71

Q4 2018

Shares 161,000 Value ($000) $11,497 Avg Close $95.81 Range $64.72 - $125.59

Q3 2018

Shares 156,500 Value ($000) $19,242 Avg Close $113.46 Range $96.98 - $126.98

Q2 2018

Shares 156,500 Value ($000) $15,375 Avg Close $89.51 Range $74.34 - $106.26

Q1 2018

Shares 153,700 Value ($000) $12,746 Avg Close $84.45 Range $74.12 - $92.98

Q4 2017

Shares 150,200 Value ($000) $11,654 Avg Close $68.21 Range $57.71 - $78.05

Q3 2017

Shares 147,300 Value ($000) $9,027 Avg Close $52.77 Range $44.75 - $61.51

Q2 2017

Shares 145,400 Value ($000) $6,688 Avg Close $48.51 Range $39.21 - $55.38

Q1 2017

Shares 143,600 Value ($000) $6,218 Avg Close $42.84 Range $38.38 - $47.43

Q4 2016

Shares 142,600 Value ($000) $5,519 Avg Close $45.27 Range $37.35 - $54.91

Q3 2016

Shares 140,200 Value ($000) $7,100 Avg Close $49.80 Range $44.69 - $55.15

Q2 2016

Shares 142,000 Value ($000) $6,454 Avg Close $46.04 Range $39.01 - $53.00

Q1 2016

Shares 142,000 Value ($000) $5,420 Avg Close $39.68 Range $31.25 - $55.94

Q4 2015

Shares 113,200 Value ($000) $6,404 Avg Close $50.83 Range $37.76 - $58.46

Q3 2015

Shares 112,600 Value ($000) $4,480 Avg Close $48.33 Range $33.61 - $56.97

Q2 2015

Shares 97,100 Value ($000) $4,637 Avg Close $42.40 Range $32.67 - $49.49

Q1 2015

Shares 91,900 Value ($000) $3,649 Avg Close $35.77 Range $19.68 - $45.36

Q4 2014

Shares 84,000 Value ($000) $1,877 Avg Close $18.95 Range $15.20 - $24.86

Q3 2014

Shares 82,000 Value ($000) $1,285 Avg Close $14.95 Range $12.63 - $17.00

Q2 2014

Shares 83,900 Value ($000) $1,245 Avg Close $14.11 Range $12.17 - $16.47

Q1 2014

Shares 83,900 Value ($000) $1,351 Avg Close $17.10 Range $9.19 - $20.29

Q4 2013

Shares 59,400 Value ($000) $555 Avg Close $9.76 Range $8.57 - $11.88

Q3 2013

Shares 59,400 Value ($000) $672 Avg Close $13.75 Range $10.42 - $16.74

Q2 2013

Shares 62,400 Value ($000) $835 Avg Close $12.28 Range $10.87 - $14.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	271,800	$38,549	$144.87	$133.61 - $160.18
Q3 2025	285,300	$40,050	$135.50	$123.67 - $148.00
Q2 2025	299,400	$37,632	$114.68	$84.23 - $130.46
Q1 2025	285,500	$31,576	$126.68	$105.18 - $154.61
Q4 2024	285,300	$38,943	$123.68	$110.95 - $140.00
Q3 2024	298,700	$34,416	$137.09	$114.08 - $157.98
Q2 2024	294,600	$40,558	$137.14	$129.33 - $145.78
Q1 2024	294,200	$40,576	$136.57	$128.00 - $148.37
Q4 2023	305,300	$40,226	$115.11	$103.63 - $133.64
Q3 2023	313,800	$35,303	$105.30	$93.28 - $119.29
Q2 2023	352,200	$33,212	$97.71	$89.04 - $107.98
Q1 2023	380,500	$38,514	$104.06	$92.89 - $125.02
Q4 2022	388,700	$46,426	$117.13	$105.14 - $129.29
Q3 2022	414,227	$43,995	$101.46	$91.53 - $109.26
Q2 2022	412,927	$40,252	$92.29	$75.25 - $100.73
Q1 2022	410,827	$38,515	$84.75	$71.88 - $95.87
Q4 2021	359,627	$30,629	$91.99	$78.31 - $108.02
Q3 2021	372,927	$35,767	$94.46	$84.77 - $101.43
Q2 2021	383,027	$37,276	$95.85	$87.19 - $103.72
Q1 2021	340,700	$33,133	$104.86	$87.37 - $120.27
Q4 2020	334,600	$32,071	$96.59	$86.02 - $108.93
Q3 2020	343,400	$33,021	$115.68	$95.42 - $136.26
Q2 2020	346,800	$42,310	$110.51	$82.51 - $131.00
Q1 2020	339,500	$29,384	$97.87	$72.14 - $115.24
Q4 2019	274,300	$29,485	$104.70	$84.68 - $119.65
Q3 2019	171,800	$15,481	$93.43	$83.19 - $102.51
Q2 2019	168,900	$14,260	$82.11	$71.85 - $91.98
Q1 2019	165,200	$14,554	$83.58	$67.10 - $92.71
Q4 2018	161,000	$11,497	$95.81	$64.72 - $125.59
Q3 2018	156,500	$19,242	$113.46	$96.98 - $126.98
Q2 2018	156,500	$15,375	$89.51	$74.34 - $106.26
Q1 2018	153,700	$12,746	$84.45	$74.12 - $92.98
Q4 2017	150,200	$11,654	$68.21	$57.71 - $78.05
Q3 2017	147,300	$9,027	$52.77	$44.75 - $61.51
Q2 2017	145,400	$6,688	$48.51	$39.21 - $55.38
Q1 2017	143,600	$6,218	$42.84	$38.38 - $47.43
Q4 2016	142,600	$5,519	$45.27	$37.35 - $54.91
Q3 2016	140,200	$7,100	$49.80	$44.69 - $55.15
Q2 2016	142,000	$6,454	$46.04	$39.01 - $53.00
Q1 2016	142,000	$5,420	$39.68	$31.25 - $55.94
Q4 2015	113,200	$6,404	$50.83	$37.76 - $58.46
Q3 2015	112,600	$4,480	$48.33	$33.61 - $56.97
Q2 2015	97,100	$4,637	$42.40	$32.67 - $49.49
Q1 2015	91,900	$3,649	$35.77	$19.68 - $45.36
Q4 2014	84,000	$1,877	$18.95	$15.20 - $24.86
Q3 2014	82,000	$1,285	$14.95	$12.63 - $17.00
Q2 2014	83,900	$1,245	$14.11	$12.17 - $16.47
Q1 2014	83,900	$1,351	$17.10	$9.19 - $20.29
Q4 2013	59,400	$555	$9.76	$8.57 - $11.88
Q3 2013	59,400	$672	$13.75	$10.42 - $16.74
Q2 2013	62,400	$835	$12.28	$10.87 - $14.06