NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

Federation des caisses Desjardins du Quebec's Holding History (CIK: 0002022297)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 104,107 Value ($000) $14,765 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 103,474 Value ($000) $14,526 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 113,130 Value ($000) $14,222 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 115,660 Value ($000) $12,793 Avg Close $126.68 Range $105.18 - $154.61

Q4 2024

Shares 127,167 Value ($000) $17,355 Avg Close $123.68 Range $110.95 - $140.00

Q3 2024

Shares 139,503 Value ($000) $16,071 Avg Close $137.09 Range $114.08 - $157.98

Q2 2024

Shares 109,735 Value ($000) $15,107 Avg Close $137.14 Range $129.33 - $145.78

Q1 2024

Shares 113,364 Value ($000) $15,631 Avg Close $136.57 Range $128.00 - $148.37

Q4 2023

Shares 171,768 Value ($000) $22,632 Avg Close $115.11 Range $103.63 - $133.64

Q3 2023

Shares 176,413 Value ($000) $19,846 Avg Close $105.30 Range $93.28 - $119.29

Q2 2023

Shares 174,415 Value ($000) $16,447 Avg Close $97.71 Range $89.04 - $107.98

Q1 2023

Shares 9,510 Value ($000) $963 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 1,303 Value ($000) $156 Avg Close $117.13 Range $105.14 - $129.29

Q3 2022

Shares 970 Value ($000) $103 Avg Close $101.46 Range $91.53 - $109.26

Q2 2022

Shares 970 Value ($000) $95 Avg Close $92.29 Range $75.25 - $100.73

Q1 2021

Shares 415 Value ($000) $40 Avg Close $104.86 Range $87.37 - $120.27

Q4 2020

Shares 415 Value ($000) $40 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 3 Value ($000) $0 Avg Close $115.68 Range $95.42 - $136.26

Q1 2020

Shares 8 Value ($000) $1 Avg Close $97.87 Range $72.14 - $115.24

Q4 2019

Shares 8 Value ($000) $1 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 8 Value ($000) $1 Avg Close $93.43 Range $83.19 - $102.51

Q3 2018

Shares 778 Value ($000) $96 Avg Close $113.46 Range $96.98 - $126.98

Q1 2018

Shares 475 Value ($000) $39 Avg Close $84.45 Range $74.12 - $92.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	104,107	$14,765	$144.87	$133.61 - $160.18
Q3 2025	103,474	$14,526	$135.50	$123.67 - $148.00
Q2 2025	113,130	$14,222	$114.68	$84.23 - $130.46
Q1 2025	115,660	$12,793	$126.68	$105.18 - $154.61
Q4 2024	127,167	$17,355	$123.68	$110.95 - $140.00
Q3 2024	139,503	$16,071	$137.09	$114.08 - $157.98
Q2 2024	109,735	$15,107	$137.14	$129.33 - $145.78
Q1 2024	113,364	$15,631	$136.57	$128.00 - $148.37
Q4 2023	171,768	$22,632	$115.11	$103.63 - $133.64
Q3 2023	176,413	$19,846	$105.30	$93.28 - $119.29
Q2 2023	174,415	$16,447	$97.71	$89.04 - $107.98
Q1 2023	9,510	$963	$104.06	$92.89 - $125.02
Q4 2022	1,303	$156	$117.13	$105.14 - $129.29
Q3 2022	970	$103	$101.46	$91.53 - $109.26
Q2 2022	970	$95	$92.29	$75.25 - $100.73
Q1 2021	415	$40	$104.86	$87.37 - $120.27
Q4 2020	415	$40	$96.59	$86.02 - $108.93
Q3 2020	3	$0	$115.68	$95.42 - $136.26
Q1 2020	8	$1	$97.87	$72.14 - $115.24
Q4 2019	8	$1	$104.70	$84.68 - $119.65
Q3 2019	8	$1	$93.43	$83.19 - $102.51
Q3 2018	778	$96	$113.46	$96.98 - $126.98
Q1 2018	475	$39	$84.45	$74.12 - $92.98