NUVALENT INC

Ticker: NUVL CUSIP: 670703107 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 8,959 Value ($000) $684 Avg Close $73.17 Range $55.53 - $82.09

Q1 2025

Shares 159,123 Value ($000) $11,285 Avg Close $78.19 Range $64.75 - $91.50

Q4 2024

Shares 213,882 Value ($000) $16,743 Avg Close $93.39 Range $76.67 - $106.32

Q3 2024

Shares 262,388 Value ($000) $26,842 Avg Close $82.95 Range $64.67 - $113.51

Q2 2024

Shares 282,662 Value ($000) $21,443 Avg Close $71.13 Range $61.80 - $83.35

Q1 2024

Shares 33,749 Value ($000) $2,534 Avg Close $79.58 Range $68.95 - $89.39

Q4 2023

Shares 15,100 Value ($000) $1,111 Avg Close $61.88 Range $41.16 - $80.94

Q3 2023

Shares 15,100 Value ($000) $694 Avg Close $44.38 Range $38.78 - $50.59

Q2 2023

Shares 15,100 Value ($000) $637 Avg Close $37.81 Range $23.09 - $45.25

Q1 2023

Shares 13,100 Value ($000) $342 Avg Close $29.57 Range $24.95 - $35.38

Q4 2022

Shares 26,732 Value ($000) $796 Avg Close $27.89 Range $17.75 - $40.43

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	8,959	$684	$73.17	$55.53 - $82.09
Q1 2025	159,123	$11,285	$78.19	$64.75 - $91.50
Q4 2024	213,882	$16,743	$93.39	$76.67 - $106.32
Q3 2024	262,388	$26,842	$82.95	$64.67 - $113.51
Q2 2024	282,662	$21,443	$71.13	$61.80 - $83.35
Q1 2024	33,749	$2,534	$79.58	$68.95 - $89.39
Q4 2023	15,100	$1,111	$61.88	$41.16 - $80.94
Q3 2023	15,100	$694	$44.38	$38.78 - $50.59
Q2 2023	15,100	$637	$37.81	$23.09 - $45.25
Q1 2023	13,100	$342	$29.57	$24.95 - $35.38
Q4 2022	26,732	$796	$27.89	$17.75 - $40.43