NUVALENT INC

Ticker: NUVL CUSIP: 670703107 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,880,057 Value ($000) $189,115 Avg Close $98.60 Range $81.02 - $112.88

Q3 2025

Shares 1,246,456 Value ($000) $107,794 Avg Close $79.06 Range $71.13 - $86.83

Q3 2024

Shares 176,281 Value ($000) $18,034 Avg Close $82.95 Range $64.67 - $113.51

Q2 2024

Shares 119,789 Value ($000) $9,087 Avg Close $71.13 Range $61.80 - $83.35

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,880,057	$189,115	$98.60	$81.02 - $112.88
Q3 2025	1,246,456	$107,794	$79.06	$71.13 - $86.83
Q3 2024	176,281	$18,034	$82.95	$64.67 - $113.51
Q2 2024	119,789	$9,087	$71.13	$61.80 - $83.35