OCERA THERAPEUTICS INC

CUSIP: 67552A108 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 186,800 Value ($000) $549 Avg Close — Range —
Q4 2015
Shares 550,000 Value ($000) $1,716 Avg Close — Range —
Q3 2015
Shares 500,000 Value ($000) $1,580 Avg Close — Range —
Q1 2015
Shares 321,254 Value ($000) $1,513 Avg Close — Range —
Q4 2014
Shares 421,254 Value ($000) $2,683 Avg Close — Range —
Q3 2014
Shares 321,254 Value ($000) $1,574 Avg Close — Range —
Q2 2014
Shares 127,048 Value ($000) $971 Avg Close — Range —
Q1 2014
Shares 121,148 Value ($000) $1,278 Avg Close — Range —
Q4 2013
Shares 14,881 Value ($000) $193 Avg Close — Range —