OCULAR THERAPEUTIX INC

Ticker: OCUL CUSIP: 67576A100 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 380,713 Value ($000) $4,622 Avg Close $12.15 Range $10.30 - $16.44

Q3 2025

Shares 234,213 Value ($000) $2,738 Avg Close $11.96 Range $9.04 - $13.85

Q2 2025

Shares 110,832 Value ($000) $1,029 Avg Close $7.83 Range $5.80 - $10.00

Q1 2025

Shares 461,230 Value ($000) $3,381 Avg Close $7.69 Range $5.79 - $9.22

Q4 2024

Shares 252,939 Value ($000) $2,160 Avg Close $9.76 Range $8.12 - $11.78

Q3 2024

Shares 207,421 Value ($000) $1,805 Avg Close $8.24 Range $6.42 - $9.39

Q2 2024

Shares 536,119 Value ($000) $3,667 Avg Close $6.17 Range $4.06 - $9.10

Q1 2024

Shares 19,413 Value ($000) $177 Avg Close $7.10 Range $3.76 - $11.31

Q4 2023

Shares 111,000 Value ($000) $495 Avg Close $2.96 Range $2.00 - $4.72

Q3 2023

Shares 116,100 Value ($000) $365 Avg Close $4.09 Range $3.06 - $5.20

Q2 2023

Shares 136,300 Value ($000) $703 Avg Close $5.95 Range $4.45 - $7.96

Q1 2023

Shares 323,424 Value ($000) $1,704 Avg Close $4.75 Range $2.77 - $6.49

Q4 2022

Shares 189,085 Value ($000) $531 Avg Close $3.31 Range $2.57 - $4.62

Q3 2022

Shares 197,760 Value ($000) $821 Avg Close $5.04 Range $3.95 - $6.53

Q1 2022

Shares 483,284 Value ($000) $2,392 Avg Close $5.54 Range $4.71 - $7.38

Q4 2021

Shares 469,866 Value ($000) $3,275 Avg Close $7.77 Range $6.02 - $12.50

Q3 2021

Shares 895,400 Value ($000) $8,954 Avg Close $11.23 Range $9.56 - $14.49

Q2 2021

Shares 1,036,045 Value ($000) $14,691 Avg Close $15.20 Range $12.92 - $19.84

Q1 2021

Shares 1,168,458 Value ($000) $19,174 Avg Close $19.26 Range $15.13 - $23.68

Q4 2020

Shares 920,295 Value ($000) $19,050 Avg Close $14.85 Range $7.67 - $24.30

Q3 2020

Shares 330,300 Value ($000) $2,514 Avg Close $8.30 Range $7.14 - $9.99

Q2 2020

Shares 188,915 Value ($000) $1,574 Avg Close $6.63 Range $4.31 - $9.24

Q1 2020

Shares 24,361 Value ($000) $121 Avg Close $4.94 Range $3.77 - $8.12

Q1 2019

Shares 30,737 Value ($000) $122 Avg Close $4.02 Range $3.46 - $5.00

Q4 2018

Shares 70,181 Value ($000) $279 Avg Close $5.51 Range $3.55 - $7.31

Q3 2018

Shares 18,995 Value ($000) $131 Avg Close $6.28 Range $5.23 - $7.17

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	380,713	$4,622	$12.15	$10.30 - $16.44
Q3 2025	234,213	$2,738	$11.96	$9.04 - $13.85
Q2 2025	110,832	$1,029	$7.83	$5.80 - $10.00
Q1 2025	461,230	$3,381	$7.69	$5.79 - $9.22
Q4 2024	252,939	$2,160	$9.76	$8.12 - $11.78
Q3 2024	207,421	$1,805	$8.24	$6.42 - $9.39
Q2 2024	536,119	$3,667	$6.17	$4.06 - $9.10
Q1 2024	19,413	$177	$7.10	$3.76 - $11.31
Q4 2023	111,000	$495	$2.96	$2.00 - $4.72
Q3 2023	116,100	$365	$4.09	$3.06 - $5.20
Q2 2023	136,300	$703	$5.95	$4.45 - $7.96
Q1 2023	323,424	$1,704	$4.75	$2.77 - $6.49
Q4 2022	189,085	$531	$3.31	$2.57 - $4.62
Q3 2022	197,760	$821	$5.04	$3.95 - $6.53
Q1 2022	483,284	$2,392	$5.54	$4.71 - $7.38
Q4 2021	469,866	$3,275	$7.77	$6.02 - $12.50
Q3 2021	895,400	$8,954	$11.23	$9.56 - $14.49
Q2 2021	1,036,045	$14,691	$15.20	$12.92 - $19.84
Q1 2021	1,168,458	$19,174	$19.26	$15.13 - $23.68
Q4 2020	920,295	$19,050	$14.85	$7.67 - $24.30
Q3 2020	330,300	$2,514	$8.30	$7.14 - $9.99
Q2 2020	188,915	$1,574	$6.63	$4.31 - $9.24
Q1 2020	24,361	$121	$4.94	$3.77 - $8.12
Q1 2019	30,737	$122	$4.02	$3.46 - $5.00
Q4 2018	70,181	$279	$5.51	$3.55 - $7.31
Q3 2018	18,995	$131	$6.28	$5.23 - $7.17