OCUPHIRE PHARMA INC

Ticker: IRD CUSIP: 67577R102 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 10,200 Value ($000) $17 Avg Close $1.24 Range $0.90 - $1.87

Q3 2022

Shares 18,200 Value ($000) $37 Avg Close $2.16 Range $1.81 - $2.80

Q2 2022

Shares 152,400 Value ($000) $293 Avg Close $2.27 Range $1.78 - $3.37

Q1 2022

Shares 246,600 Value ($000) $799 Avg Close $3.42 Range $2.59 - $4.43

Q4 2021

Shares 318,100 Value ($000) $1,187 Avg Close $4.01 Range $3.19 - $5.50

Q3 2021

Shares 43,900 Value ($000) $226 Avg Close $4.61 Range $3.82 - $5.65

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	10,200	$17	$1.24	$0.90 - $1.87
Q3 2022	18,200	$37	$2.16	$1.81 - $2.80
Q2 2022	152,400	$293	$2.27	$1.78 - $3.37
Q1 2022	246,600	$799	$3.42	$2.59 - $4.43
Q4 2021	318,100	$1,187	$4.01	$3.19 - $5.50
Q3 2021	43,900	$226	$4.61	$3.82 - $5.65