ONCOTHYREON INC

CUSIP: 682324108 Class: CMN

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 428,000 Value ($000) $813 Avg Close — Range —
Q3 2014
Shares 428,000 Value ($000) $822 Avg Close — Range —
Q2 2014
Shares 738,336 Value ($000) $2,392 Avg Close — Range —
Q1 2014
Shares 738,336 Value ($000) $2,208 Avg Close — Range —
Q4 2013
Shares 748,336 Value ($000) $1,317 Avg Close — Range —