OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

CENTRAL TRUST Co's Holding History (CIK: 0000044365)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017

Shares 500 Value ($000) $3 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 500 Value ($000) $3 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 500 Value ($000) $4 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 500 Value ($000) $5 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 6,000 Value ($000) $64 Avg Close $9.96 Range $8.91 - $11.31

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2017	500	$3	$6.31	$5.85 - $7.24
Q2 2017	500	$3	$7.01	$5.99 - $8.04
Q1 2017	500	$4	$8.42	$7.13 - $9.55
Q4 2016	500	$5	$10.35	$8.92 - $12.15
Q3 2016	6,000	$64	$9.96	$8.91 - $11.31