OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

WELLS FARGO & COMPANY/MN's Holding History (CIK: 0000072971)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 468,518 Value ($000) $590 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 342,486 Value ($000) $531 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 271,094 Value ($000) $358 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 230,015 Value ($000) $382 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 229,262 Value ($000) $337 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 199,524 Value ($000) $297 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 198,557 Value ($000) $248 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 202,428 Value ($000) $243 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 185,805 Value ($000) $281 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 171,123 Value ($000) $274 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 259,380 Value ($000) $563 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 175,273 Value ($000) $256 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 70,765 Value ($000) $88 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 73,391 Value ($000) $139 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 83,105 Value ($000) $209 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 470,228 Value ($000) $1,617 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 685,660 Value ($000) $3,298 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 1,020,452 Value ($000) $3,725 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 978,457 Value ($000) $3,963 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 959,419 Value ($000) $4,116 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 1,559,598 Value ($000) $6,160 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 851,497 Value ($000) $3,143 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 916,589 Value ($000) $3,126 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 881,360 Value ($000) $1,181 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 716,385 Value ($000) $1,053 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 1,515,369 Value ($000) $3,167 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 1,476,702 Value ($000) $3,603 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 1,497,570 Value ($000) $3,908 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 894,895 Value ($000) $2,693 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 337,868 Value ($000) $1,169 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 323,963 Value ($000) $1,523 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 537,283 Value ($000) $1,703 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 487,963 Value ($000) $2,390 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 481,085 Value ($000) $3,300 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 420,908 Value ($000) $2,769 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 699,650 Value ($000) $5,597 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 409,566 Value ($000) $3,809 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 464,985 Value ($000) $4,924 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 421,351 Value ($000) $3,935 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 543,853 Value ($000) $5,651 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 479,031 Value ($000) $4,814 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 341,494 Value ($000) $2,872 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 217,134 Value ($000) $3,502 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 90,817 Value ($000) $1,286 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 91,334 Value ($000) $913 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 95,425 Value ($000) $812 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 96,566 Value ($000) $854 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 72,347 Value ($000) $674 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 44,620 Value ($000) $377 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 51,550 Value ($000) $454 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 54,750 Value ($000) $389 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	468,518	$590	$1.39	$1.22 - $1.60
Q3 2025	342,486	$531	$1.37	$1.11 - $1.55
Q2 2025	271,094	$358	$1.37	$1.21 - $1.69
Q1 2025	230,015	$382	$1.65	$1.43 - $2.04
Q4 2024	229,262	$337	$1.53	$1.37 - $1.76
Q3 2024	199,524	$297	$1.48	$1.19 - $1.75
Q2 2024	198,557	$248	$1.30	$1.15 - $1.45
Q1 2024	202,428	$243	$1.00	$0.85 - $1.57
Q4 2023	185,805	$281	$1.45	$1.20 - $1.66
Q3 2023	171,123	$274	$1.82	$1.48 - $2.24
Q2 2023	259,380	$563	$1.56	$1.34 - $2.24
Q1 2023	175,273	$256	$1.29	$1.00 - $1.68
Q4 2022	70,765	$88	$1.58	$1.03 - $2.01
Q3 2022	73,391	$139	$2.36	$1.78 - $2.86
Q2 2022	83,105	$209	$2.92	$2.17 - $3.63
Q1 2022	470,228	$1,617	$3.53	$2.79 - $4.96
Q4 2021	685,660	$3,298	$4.05	$3.49 - $5.25
Q3 2021	1,020,452	$3,725	$3.72	$3.26 - $4.24
Q2 2021	978,457	$3,963	$3.92	$3.32 - $4.63
Q1 2021	959,419	$4,116	$4.78	$3.83 - $6.27
Q4 2020	1,559,598	$6,160	$4.18	$3.02 - $4.92
Q3 2020	851,497	$3,143	$4.22	$2.84 - $6.47
Q2 2020	916,589	$3,126	$2.24	$1.12 - $3.52
Q1 2020	881,360	$1,181	$1.57	$1.30 - $2.91
Q4 2019	716,385	$1,053	$1.67	$1.33 - $2.43
Q3 2019	1,515,369	$3,167	$2.04	$1.75 - $2.53
Q2 2019	1,476,702	$3,603	$2.18	$1.73 - $2.64
Q1 2019	1,497,570	$3,908	$3.03	$2.40 - $3.94
Q4 2018	894,895	$2,693	$3.39	$2.34 - $3.92
Q3 2018	337,868	$1,169	$5.26	$3.21 - $6.40
Q2 2018	323,963	$1,523	$3.79	$2.91 - $5.02
Q1 2018	537,283	$1,703	$4.03	$2.66 - $5.14
Q4 2017	487,963	$2,390	$5.80	$4.50 - $7.08
Q3 2017	481,085	$3,300	$6.31	$5.85 - $7.24
Q2 2017	420,908	$2,769	$7.01	$5.99 - $8.04
Q1 2017	699,650	$5,597	$8.42	$7.13 - $9.55
Q4 2016	409,566	$3,809	$10.35	$8.92 - $12.15
Q3 2016	464,985	$4,924	$9.96	$8.91 - $11.31
Q2 2016	421,351	$3,935	$10.16	$8.71 - $11.39
Q1 2016	543,853	$5,651	$9.14	$7.12 - $11.85
Q4 2015	479,031	$4,814	$10.02	$8.20 - $11.49
Q3 2015	341,494	$2,872	$13.24	$8.23 - $17.51
Q2 2015	217,134	$3,502	$15.55	$13.71 - $19.20
Q1 2015	90,817	$1,286	$13.01	$9.81 - $15.23
Q4 2014	91,334	$913	$8.56	$8.02 - $10.16
Q3 2014	95,425	$812	$8.79	$8.09 - $9.62
Q2 2014	96,566	$854	$8.73	$7.82 - $9.83
Q1 2014	72,347	$674	$8.77	$7.32 - $10.25
Q4 2013	44,620	$377	$10.11	$8.17 - $12.95
Q3 2013	51,550	$454	$8.02	$7.13 - $10.00
Q2 2013	54,750	$389	$6.91	$6.14 - $7.65