OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

PRICE T ROWE ASSOCIATES INC /MD/'s Holding History (CIK: 0000080255)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 367,191 Value ($000) $0 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 343,286 Value ($000) $1 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 437,506 Value ($000) $1 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 501,668 Value ($000) $1 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 455,521 Value ($000) $1 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 436,950 Value ($000) $1 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 433,048 Value ($000) $1 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 445,981 Value ($000) $1 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 428,310 Value ($000) $1 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 399,193 Value ($000) $1 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 410,192 Value ($000) $1 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 405,029 Value ($000) $1 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 357,797 Value ($000) $0 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 272,058 Value ($000) $515 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 275,601 Value ($000) $697 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 272,505 Value ($000) $937 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 284,674 Value ($000) $1,369 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 284,674 Value ($000) $1,039 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 284,674 Value ($000) $1,153 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 292,197 Value ($000) $1,254 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 245,170 Value ($000) $968 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 171,140 Value ($000) $632 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 55,220 Value ($000) $188 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 243,366 Value ($000) $326 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 98,689 Value ($000) $145 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 258,322 Value ($000) $540 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 256,507 Value ($000) $626 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 255,426 Value ($000) $667 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 253,046 Value ($000) $762 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 111,065 Value ($000) $384 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 73,347 Value ($000) $345 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 58,746 Value ($000) $186 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 58,193 Value ($000) $285 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 67,793 Value ($000) $465 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 67,793 Value ($000) $446 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 976,163 Value ($000) $7,809 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 888,801 Value ($000) $8,266 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 947,871 Value ($000) $10,038 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 919,171 Value ($000) $8,585 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 923,171 Value ($000) $9,592 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 964,521 Value ($000) $9,693 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 905,500 Value ($000) $7,615 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 845,700 Value ($000) $13,599 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 671,700 Value ($000) $9,518 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 563,900 Value ($000) $5,633 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 452,600 Value ($000) $3,852 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 425,000 Value ($000) $3,757 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 332,000 Value ($000) $3,094 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 311,300 Value ($000) $2,627 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 34,700 Value ($000) $306 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 15,900 Value ($000) $113 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	367,191	$0	$1.39	$1.22 - $1.60
Q3 2025	343,286	$1	$1.37	$1.11 - $1.55
Q2 2025	437,506	$1	$1.37	$1.21 - $1.69
Q1 2025	501,668	$1	$1.65	$1.43 - $2.04
Q4 2024	455,521	$1	$1.53	$1.37 - $1.76
Q3 2024	436,950	$1	$1.48	$1.19 - $1.75
Q2 2024	433,048	$1	$1.30	$1.15 - $1.45
Q1 2024	445,981	$1	$1.00	$0.85 - $1.57
Q4 2023	428,310	$1	$1.45	$1.20 - $1.66
Q3 2023	399,193	$1	$1.82	$1.48 - $2.24
Q2 2023	410,192	$1	$1.56	$1.34 - $2.24
Q1 2023	405,029	$1	$1.29	$1.00 - $1.68
Q4 2022	357,797	$0	$1.58	$1.03 - $2.01
Q3 2022	272,058	$515	$2.36	$1.78 - $2.86
Q2 2022	275,601	$697	$2.92	$2.17 - $3.63
Q1 2022	272,505	$937	$3.53	$2.79 - $4.96
Q4 2021	284,674	$1,369	$4.05	$3.49 - $5.25
Q3 2021	284,674	$1,039	$3.72	$3.26 - $4.24
Q2 2021	284,674	$1,153	$3.92	$3.32 - $4.63
Q1 2021	292,197	$1,254	$4.78	$3.83 - $6.27
Q4 2020	245,170	$968	$4.18	$3.02 - $4.92
Q3 2020	171,140	$632	$4.22	$2.84 - $6.47
Q2 2020	55,220	$188	$2.24	$1.12 - $3.52
Q1 2020	243,366	$326	$1.57	$1.30 - $2.91
Q4 2019	98,689	$145	$1.67	$1.33 - $2.43
Q3 2019	258,322	$540	$2.04	$1.75 - $2.53
Q2 2019	256,507	$626	$2.18	$1.73 - $2.64
Q1 2019	255,426	$667	$3.03	$2.40 - $3.94
Q4 2018	253,046	$762	$3.39	$2.34 - $3.92
Q3 2018	111,065	$384	$5.26	$3.21 - $6.40
Q2 2018	73,347	$345	$3.79	$2.91 - $5.02
Q1 2018	58,746	$186	$4.03	$2.66 - $5.14
Q4 2017	58,193	$285	$5.80	$4.50 - $7.08
Q3 2017	67,793	$465	$6.31	$5.85 - $7.24
Q2 2017	67,793	$446	$7.01	$5.99 - $8.04
Q1 2017	976,163	$7,809	$8.42	$7.13 - $9.55
Q4 2016	888,801	$8,266	$10.35	$8.92 - $12.15
Q3 2016	947,871	$10,038	$9.96	$8.91 - $11.31
Q2 2016	919,171	$8,585	$10.16	$8.71 - $11.39
Q1 2016	923,171	$9,592	$9.14	$7.12 - $11.85
Q4 2015	964,521	$9,693	$10.02	$8.20 - $11.49
Q3 2015	905,500	$7,615	$13.24	$8.23 - $17.51
Q2 2015	845,700	$13,599	$15.55	$13.71 - $19.20
Q1 2015	671,700	$9,518	$13.01	$9.81 - $15.23
Q4 2014	563,900	$5,633	$8.56	$8.02 - $10.16
Q3 2014	452,600	$3,852	$8.79	$8.09 - $9.62
Q2 2014	425,000	$3,757	$8.73	$7.82 - $9.83
Q1 2014	332,000	$3,094	$8.77	$7.32 - $10.25
Q4 2013	311,300	$2,627	$10.11	$8.17 - $12.95
Q3 2013	34,700	$306	$8.02	$7.13 - $10.00
Q2 2013	15,900	$113	$6.91	$6.14 - $7.65