OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

DIMENSIONAL FUND ADVISORS LP's Holding History (CIK: 0000354204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,611,318 Value ($000) $2,031 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 1,667,368 Value ($000) $2,582 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 1,929,683 Value ($000) $2,547 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 2,222,512 Value ($000) $3,690 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 2,268,666 Value ($000) $3,335 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 2,328,580 Value ($000) $3,471 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 2,654,535 Value ($000) $3,319 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 2,921,436 Value ($000) $3,506 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 3,449,062 Value ($000) $5,210 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 4,313,492 Value ($000) $6,899 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 3,754,290 Value ($000) $8,141 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 6,880,047 Value ($000) $10,043 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 8,956,810 Value ($000) $11 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 10,823,641 Value ($000) $20,456 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 9,078,680 Value ($000) $22,970 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 7,184,414 Value ($000) $24,717 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 4,147,094 Value ($000) $19,948 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 4,473,095 Value ($000) $16,327 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 7,232,279 Value ($000) $29,292 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 7,392,557 Value ($000) $31,639 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 5,612,566 Value ($000) $22,172 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 5,081,906 Value ($000) $18,742 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 5,107,679 Value ($000) $17,400 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 4,404,818 Value ($000) $5,903 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 4,419,633 Value ($000) $6,497 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 4,699,384 Value ($000) $9,822 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 4,564,352 Value ($000) $11,135 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 4,329,742 Value ($000) $11,300 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 4,163,164 Value ($000) $12,533 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 4,440,784 Value ($000) $15,363 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 3,543,378 Value ($000) $16,655 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 3,577,414 Value ($000) $11,340 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 3,708,089 Value ($000) $18,170 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 4,003,643 Value ($000) $27,466 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 1,762,540 Value ($000) $11,598 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 1,621,128 Value ($000) $12,968 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 1,589,903 Value ($000) $14,811 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 1,559,052 Value ($000) $16,511 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 1,477,212 Value ($000) $13,797 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 1,036,512 Value ($000) $10,765 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 901,675 Value ($000) $9,063 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 2,423,890 Value ($000) $20,386 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 1,307,905 Value ($000) $21,027 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 1,251,393 Value ($000) $17,737 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 1,173,311 Value ($000) $11,720 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 1,128,905 Value ($000) $9,609 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 1,208,901 Value ($000) $10,689 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 1,447,523 Value ($000) $13,488 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 1,864,729 Value ($000) $15,739 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 1,304,145 Value ($000) $11,488 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 1,577,337 Value ($000) $11,200 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,611,318	$2,031	$1.39	$1.22 - $1.60
Q3 2025	1,667,368	$2,582	$1.37	$1.11 - $1.55
Q2 2025	1,929,683	$2,547	$1.37	$1.21 - $1.69
Q1 2025	2,222,512	$3,690	$1.65	$1.43 - $2.04
Q4 2024	2,268,666	$3,335	$1.53	$1.37 - $1.76
Q3 2024	2,328,580	$3,471	$1.48	$1.19 - $1.75
Q2 2024	2,654,535	$3,319	$1.30	$1.15 - $1.45
Q1 2024	2,921,436	$3,506	$1.00	$0.85 - $1.57
Q4 2023	3,449,062	$5,210	$1.45	$1.20 - $1.66
Q3 2023	4,313,492	$6,899	$1.82	$1.48 - $2.24
Q2 2023	3,754,290	$8,141	$1.56	$1.34 - $2.24
Q1 2023	6,880,047	$10,043	$1.29	$1.00 - $1.68
Q4 2022	8,956,810	$11	$1.58	$1.03 - $2.01
Q3 2022	10,823,641	$20,456	$2.36	$1.78 - $2.86
Q2 2022	9,078,680	$22,970	$2.92	$2.17 - $3.63
Q1 2022	7,184,414	$24,717	$3.53	$2.79 - $4.96
Q4 2021	4,147,094	$19,948	$4.05	$3.49 - $5.25
Q3 2021	4,473,095	$16,327	$3.72	$3.26 - $4.24
Q2 2021	7,232,279	$29,292	$3.92	$3.32 - $4.63
Q1 2021	7,392,557	$31,639	$4.78	$3.83 - $6.27
Q4 2020	5,612,566	$22,172	$4.18	$3.02 - $4.92
Q3 2020	5,081,906	$18,742	$4.22	$2.84 - $6.47
Q2 2020	5,107,679	$17,400	$2.24	$1.12 - $3.52
Q1 2020	4,404,818	$5,903	$1.57	$1.30 - $2.91
Q4 2019	4,419,633	$6,497	$1.67	$1.33 - $2.43
Q3 2019	4,699,384	$9,822	$2.04	$1.75 - $2.53
Q2 2019	4,564,352	$11,135	$2.18	$1.73 - $2.64
Q1 2019	4,329,742	$11,300	$3.03	$2.40 - $3.94
Q4 2018	4,163,164	$12,533	$3.39	$2.34 - $3.92
Q3 2018	4,440,784	$15,363	$5.26	$3.21 - $6.40
Q2 2018	3,543,378	$16,655	$3.79	$2.91 - $5.02
Q1 2018	3,577,414	$11,340	$4.03	$2.66 - $5.14
Q4 2017	3,708,089	$18,170	$5.80	$4.50 - $7.08
Q3 2017	4,003,643	$27,466	$6.31	$5.85 - $7.24
Q2 2017	1,762,540	$11,598	$7.01	$5.99 - $8.04
Q1 2017	1,621,128	$12,968	$8.42	$7.13 - $9.55
Q4 2016	1,589,903	$14,811	$10.35	$8.92 - $12.15
Q3 2016	1,559,052	$16,511	$9.96	$8.91 - $11.31
Q2 2016	1,477,212	$13,797	$10.16	$8.71 - $11.39
Q1 2016	1,036,512	$10,765	$9.14	$7.12 - $11.85
Q4 2015	901,675	$9,063	$10.02	$8.20 - $11.49
Q3 2015	2,423,890	$20,386	$13.24	$8.23 - $17.51
Q2 2015	1,307,905	$21,027	$15.55	$13.71 - $19.20
Q1 2015	1,251,393	$17,737	$13.01	$9.81 - $15.23
Q4 2014	1,173,311	$11,720	$8.56	$8.02 - $10.16
Q3 2014	1,128,905	$9,609	$8.79	$8.09 - $9.62
Q2 2014	1,208,901	$10,689	$8.73	$7.82 - $9.83
Q1 2014	1,447,523	$13,488	$8.77	$7.32 - $10.25
Q4 2013	1,864,729	$15,739	$10.11	$8.17 - $12.95
Q3 2013	1,304,145	$11,488	$8.02	$7.13 - $10.00
Q2 2013	1,577,337	$11,200	$6.91	$6.14 - $7.65