OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

CAISSE DE DEPOT ET PLACEMENT DU QUEBEC's Holding History (CIK: 0000898286)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016

Shares 84,201 Value ($000) $875 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 84,201 Value ($000) $846 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 84,201 Value ($000) $708 Avg Close $13.24 Range $8.23 - $17.51

Q3 2014

Shares 157,653 Value ($000) $1,342 Avg Close $8.79 Range $8.09 - $9.62

Q2 2013

Shares 1,290,084 Value ($000) $9,160 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2016	84,201	$875	$9.14	$7.12 - $11.85
Q4 2015	84,201	$846	$10.02	$8.20 - $11.49
Q3 2015	84,201	$708	$13.24	$8.23 - $17.51
Q3 2014	157,653	$1,342	$8.79	$8.09 - $9.62
Q2 2013	1,290,084	$9,160	$6.91	$6.14 - $7.65