OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM's Holding History (CIK: 0000938076)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 176,260 Value ($000) $222 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 176,260 Value ($000) $273 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 176,260 Value ($000) $233 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 176,260 Value ($000) $293 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 176,260 Value ($000) $259 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 278,700 Value ($000) $415 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 176,260 Value ($000) $220 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 176,020 Value ($000) $257 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 176,260 Value ($000) $266 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 176,260 Value ($000) $282 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 176,020 Value ($000) $382 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 176,020 Value ($000) $257 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 176,020 Value ($000) $220 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 176,020 Value ($000) $333 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 346,661 Value ($000) $877 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 366,480 Value ($000) $1,261 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 302,797 Value ($000) $1,456 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 176,020 Value ($000) $642 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 176,020 Value ($000) $713 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 176,020 Value ($000) $755 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 180,390 Value ($000) $713 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 180,390 Value ($000) $666 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 180,390 Value ($000) $615 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 180,390 Value ($000) $242 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 180,850 Value ($000) $266 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 180,850 Value ($000) $378 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 180,850 Value ($000) $441 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 180,850 Value ($000) $472 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 180,850 Value ($000) $544 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 180,850 Value ($000) $626 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 180,850 Value ($000) $850 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 400,789 Value ($000) $1,271 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 400,789 Value ($000) $1,964 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 400,278 Value ($000) $2,746 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 400,278 Value ($000) $2,634 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 372,338 Value ($000) $2,979 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 372,338 Value ($000) $3,463 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 365,078 Value ($000) $3,866 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 365,078 Value ($000) $3,410 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 306,636 Value ($000) $3,186 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 222,505 Value ($000) $2,236 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 210,742 Value ($000) $1,772 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 135,656 Value ($000) $2,181 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 109,402 Value ($000) $1,550 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 103,432 Value ($000) $1,033 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 103,432 Value ($000) $880 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 103,432 Value ($000) $914 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 89,584 Value ($000) $835 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 89,584 Value ($000) $756 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 89,584 Value ($000) $789 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 89,584 Value ($000) $636 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	176,260	$222	$1.39	$1.22 - $1.60
Q3 2025	176,260	$273	$1.37	$1.11 - $1.55
Q2 2025	176,260	$233	$1.37	$1.21 - $1.69
Q1 2025	176,260	$293	$1.65	$1.43 - $2.04
Q4 2024	176,260	$259	$1.53	$1.37 - $1.76
Q3 2024	278,700	$415	$1.48	$1.19 - $1.75
Q2 2024	176,260	$220	$1.30	$1.15 - $1.45
Q1 2024	176,020	$257	$1.00	$0.85 - $1.57
Q4 2023	176,260	$266	$1.45	$1.20 - $1.66
Q3 2023	176,260	$282	$1.82	$1.48 - $2.24
Q2 2023	176,020	$382	$1.56	$1.34 - $2.24
Q1 2023	176,020	$257	$1.29	$1.00 - $1.68
Q4 2022	176,020	$220	$1.58	$1.03 - $2.01
Q3 2022	176,020	$333	$2.36	$1.78 - $2.86
Q2 2022	346,661	$877	$2.92	$2.17 - $3.63
Q1 2022	366,480	$1,261	$3.53	$2.79 - $4.96
Q4 2021	302,797	$1,456	$4.05	$3.49 - $5.25
Q3 2021	176,020	$642	$3.72	$3.26 - $4.24
Q2 2021	176,020	$713	$3.92	$3.32 - $4.63
Q1 2021	176,020	$755	$4.78	$3.83 - $6.27
Q4 2020	180,390	$713	$4.18	$3.02 - $4.92
Q3 2020	180,390	$666	$4.22	$2.84 - $6.47
Q2 2020	180,390	$615	$2.24	$1.12 - $3.52
Q1 2020	180,390	$242	$1.57	$1.30 - $2.91
Q4 2019	180,850	$266	$1.67	$1.33 - $2.43
Q3 2019	180,850	$378	$2.04	$1.75 - $2.53
Q2 2019	180,850	$441	$2.18	$1.73 - $2.64
Q1 2019	180,850	$472	$3.03	$2.40 - $3.94
Q4 2018	180,850	$544	$3.39	$2.34 - $3.92
Q3 2018	180,850	$626	$5.26	$3.21 - $6.40
Q2 2018	180,850	$850	$3.79	$2.91 - $5.02
Q1 2018	400,789	$1,271	$4.03	$2.66 - $5.14
Q4 2017	400,789	$1,964	$5.80	$4.50 - $7.08
Q3 2017	400,278	$2,746	$6.31	$5.85 - $7.24
Q2 2017	400,278	$2,634	$7.01	$5.99 - $8.04
Q1 2017	372,338	$2,979	$8.42	$7.13 - $9.55
Q4 2016	372,338	$3,463	$10.35	$8.92 - $12.15
Q3 2016	365,078	$3,866	$9.96	$8.91 - $11.31
Q2 2016	365,078	$3,410	$10.16	$8.71 - $11.39
Q1 2016	306,636	$3,186	$9.14	$7.12 - $11.85
Q4 2015	222,505	$2,236	$10.02	$8.20 - $11.49
Q3 2015	210,742	$1,772	$13.24	$8.23 - $17.51
Q2 2015	135,656	$2,181	$15.55	$13.71 - $19.20
Q1 2015	109,402	$1,550	$13.01	$9.81 - $15.23
Q4 2014	103,432	$1,033	$8.56	$8.02 - $10.16
Q3 2014	103,432	$880	$8.79	$8.09 - $9.62
Q2 2014	103,432	$914	$8.73	$7.82 - $9.83
Q1 2014	89,584	$835	$8.77	$7.32 - $10.25
Q4 2013	89,584	$756	$10.11	$8.17 - $12.95
Q3 2013	89,584	$789	$8.02	$7.13 - $10.00
Q2 2013	89,584	$636	$6.91	$6.14 - $7.65