OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

PARADIGM ASSET MANAGEMENT CO LLC's Holding History (CIK: 0001034549)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017

Shares 3,800 Value ($000) $30,400 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 11,650 Value ($000) $108,345 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 33,650 Value ($000) $356,354 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 26,200 Value ($000) $244,708 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 21,512 Value ($000) $223,510 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 20,550 Value ($000) $206,528 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 23,350 Value ($000) $196,374 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 21,900 Value ($000) $352,152 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 21,900 Value ($000) $310,323 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 59,300 Value ($000) $592,407 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 59,300 Value ($000) $504,643 Avg Close $8.79 Range $8.09 - $9.62

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2017	3,800	$30,400	$8.42	$7.13 - $9.55
Q4 2016	11,650	$108,345	$10.35	$8.92 - $12.15
Q3 2016	33,650	$356,354	$9.96	$8.91 - $11.31
Q2 2016	26,200	$244,708	$10.16	$8.71 - $11.39
Q1 2016	21,512	$223,510	$9.14	$7.12 - $11.85
Q4 2015	20,550	$206,528	$10.02	$8.20 - $11.49
Q3 2015	23,350	$196,374	$13.24	$8.23 - $17.51
Q2 2015	21,900	$352,152	$15.55	$13.71 - $19.20
Q1 2015	21,900	$310,323	$13.01	$9.81 - $15.23
Q4 2014	59,300	$592,407	$8.56	$8.02 - $10.16
Q3 2014	59,300	$504,643	$8.79	$8.09 - $9.62