OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

ING GROEP NV's Holding History (CIK: 0001039765)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 335,000 Value ($000) $1,575 Avg Close $3.79 Range $2.91 - $5.02

Q4 2017

Shares 71,168 Value ($000) $349 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 32,168 Value ($000) $221 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 47,070 Value ($000) $459 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 31,769 Value ($000) $340 Avg Close $8.42 Range $7.13 - $9.55

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	335,000	$1,575	$3.79	$2.91 - $5.02
Q4 2017	71,168	$349	$5.80	$4.50 - $7.08
Q3 2017	32,168	$221	$6.31	$5.85 - $7.24
Q2 2017	47,070	$459	$7.01	$5.99 - $8.04
Q1 2017	31,769	$340	$8.42	$7.13 - $9.55