OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

Cambridge Investment Research Advisors, Inc.'s Holding History (CIK: 0001419186)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 89,721 Value ($000) $0 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 96,511 Value ($000) $0 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 103,111 Value ($000) $0 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 103,110 Value ($000) $0 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 103,110 Value ($000) $0 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 103,561 Value ($000) $0 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 104,600 Value ($000) $0 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 105,060 Value ($000) $0 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 116,239 Value ($000) $0 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 115,949 Value ($000) $0 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 133,325 Value ($000) $0 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 131,974 Value ($000) $0 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 135,039 Value ($000) $0 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 210,316 Value ($000) $397 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 261,441 Value ($000) $661 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 262,841 Value ($000) $904 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 267,989 Value ($000) $1,289 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 287,074 Value ($000) $1,048 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 293,941 Value ($000) $1,190 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 303,722 Value ($000) $1,303 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 307,921 Value ($000) $1,216 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 368,278 Value ($000) $1,359 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 348,916 Value ($000) $1,190 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 376,616 Value ($000) $505 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 385,092 Value ($000) $566 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 413,828 Value ($000) $865 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 419,542 Value ($000) $1,024 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 423,667 Value ($000) $1,106 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 342,259 Value ($000) $1,030 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 386,602 Value ($000) $1,338 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 419,044 Value ($000) $1,970 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 448,269 Value ($000) $1,421 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 489,228 Value ($000) $2,397 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 479,443 Value ($000) $3,289 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 489,443 Value ($000) $3,221 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 503,931 Value ($000) $4,031 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 497,616 Value ($000) $4,628 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 528,062 Value ($000) $5,592 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 593,329 Value ($000) $5,542 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 676,935 Value ($000) $7,033 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 761,871 Value ($000) $7,657 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 455,012 Value ($000) $3,827 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 428,950 Value ($000) $6,898 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 400,750 Value ($000) $5,679 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 395,050 Value ($000) $3,947 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 405,272 Value ($000) $3,449 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 30,572 Value ($000) $270 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 40,972 Value ($000) $382 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 14,150 Value ($000) $119 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 61,200 Value ($000) $539 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 12,450 Value ($000) $88 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	89,721	$0	$1.39	$1.22 - $1.60
Q3 2025	96,511	$0	$1.37	$1.11 - $1.55
Q2 2025	103,111	$0	$1.37	$1.21 - $1.69
Q1 2025	103,110	$0	$1.65	$1.43 - $2.04
Q4 2024	103,110	$0	$1.53	$1.37 - $1.76
Q3 2024	103,561	$0	$1.48	$1.19 - $1.75
Q2 2024	104,600	$0	$1.30	$1.15 - $1.45
Q1 2024	105,060	$0	$1.00	$0.85 - $1.57
Q4 2023	116,239	$0	$1.45	$1.20 - $1.66
Q3 2023	115,949	$0	$1.82	$1.48 - $2.24
Q2 2023	133,325	$0	$1.56	$1.34 - $2.24
Q1 2023	131,974	$0	$1.29	$1.00 - $1.68
Q4 2022	135,039	$0	$1.58	$1.03 - $2.01
Q3 2022	210,316	$397	$2.36	$1.78 - $2.86
Q2 2022	261,441	$661	$2.92	$2.17 - $3.63
Q1 2022	262,841	$904	$3.53	$2.79 - $4.96
Q4 2021	267,989	$1,289	$4.05	$3.49 - $5.25
Q3 2021	287,074	$1,048	$3.72	$3.26 - $4.24
Q2 2021	293,941	$1,190	$3.92	$3.32 - $4.63
Q1 2021	303,722	$1,303	$4.78	$3.83 - $6.27
Q4 2020	307,921	$1,216	$4.18	$3.02 - $4.92
Q3 2020	368,278	$1,359	$4.22	$2.84 - $6.47
Q2 2020	348,916	$1,190	$2.24	$1.12 - $3.52
Q1 2020	376,616	$505	$1.57	$1.30 - $2.91
Q4 2019	385,092	$566	$1.67	$1.33 - $2.43
Q3 2019	413,828	$865	$2.04	$1.75 - $2.53
Q2 2019	419,542	$1,024	$2.18	$1.73 - $2.64
Q1 2019	423,667	$1,106	$3.03	$2.40 - $3.94
Q4 2018	342,259	$1,030	$3.39	$2.34 - $3.92
Q3 2018	386,602	$1,338	$5.26	$3.21 - $6.40
Q2 2018	419,044	$1,970	$3.79	$2.91 - $5.02
Q1 2018	448,269	$1,421	$4.03	$2.66 - $5.14
Q4 2017	489,228	$2,397	$5.80	$4.50 - $7.08
Q3 2017	479,443	$3,289	$6.31	$5.85 - $7.24
Q2 2017	489,443	$3,221	$7.01	$5.99 - $8.04
Q1 2017	503,931	$4,031	$8.42	$7.13 - $9.55
Q4 2016	497,616	$4,628	$10.35	$8.92 - $12.15
Q3 2016	528,062	$5,592	$9.96	$8.91 - $11.31
Q2 2016	593,329	$5,542	$10.16	$8.71 - $11.39
Q1 2016	676,935	$7,033	$9.14	$7.12 - $11.85
Q4 2015	761,871	$7,657	$10.02	$8.20 - $11.49
Q3 2015	455,012	$3,827	$13.24	$8.23 - $17.51
Q2 2015	428,950	$6,898	$15.55	$13.71 - $19.20
Q1 2015	400,750	$5,679	$13.01	$9.81 - $15.23
Q4 2014	395,050	$3,947	$8.56	$8.02 - $10.16
Q3 2014	405,272	$3,449	$8.79	$8.09 - $9.62
Q2 2014	30,572	$270	$8.73	$7.82 - $9.83
Q1 2014	40,972	$382	$8.77	$7.32 - $10.25
Q4 2013	14,150	$119	$10.11	$8.17 - $12.95
Q3 2013	61,200	$539	$8.02	$7.13 - $10.00
Q2 2013	12,450	$88	$6.91	$6.14 - $7.65