OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,857,433 Value ($000) $3,600 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 279,875 Value ($000) $434 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 217,395 Value ($000) $287 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 1,856,526 Value ($000) $3,082 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 3,210,290 Value ($000) $4,719 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 2,501,674 Value ($000) $3,727 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 344,333 Value ($000) $430 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 223,386 Value ($000) $268 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 408,551 Value ($000) $617 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 209,591 Value ($000) $335 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 179,604 Value ($000) $390 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 264,227 Value ($000) $386 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 1,075,629 Value ($000) $1,345 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 850,208 Value ($000) $1,607 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 1,046,418 Value ($000) $2,647 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 296,618 Value ($000) $1,020 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 828,065 Value ($000) $3,983 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 211,672 Value ($000) $773 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 291,931 Value ($000) $1,182 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 280,020 Value ($000) $1,201 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 176,440 Value ($000) $697 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 1,110,217 Value ($000) $4,097 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 7,843,629 Value ($000) $26,746 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 62,568 Value ($000) $83 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 147,490 Value ($000) $217 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 231,655 Value ($000) $484 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 243,630 Value ($000) $594 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 2,150,527 Value ($000) $5,613 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 448,207 Value ($000) $1,350 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 553,220 Value ($000) $1,915 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 451,434 Value ($000) $2,122 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 346,821 Value ($000) $1,099 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 458,032 Value ($000) $2,244 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 58,321 Value ($000) $400 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 141,238 Value ($000) $929 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 45,342 Value ($000) $363 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 197,801 Value ($000) $1,840 Avg Close $10.35 Range $8.92 - $12.15

Q2 2016

Shares 324,644 Value ($000) $3,032 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 55,142 Value ($000) $573 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 352,641 Value ($000) $3,544 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 1,319,616 Value ($000) $11,098 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 347,443 Value ($000) $5,587 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 91,434 Value ($000) $1,295 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 287,782 Value ($000) $2,875 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 110,889 Value ($000) $944 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 180,415 Value ($000) $1,595 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 4,772 Value ($000) $44 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 6,998 Value ($000) $59 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 115,440 Value ($000) $1,017 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 18,281 Value ($000) $130 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,857,433	$3,600	$1.39	$1.22 - $1.60
Q3 2025	279,875	$434	$1.37	$1.11 - $1.55
Q2 2025	217,395	$287	$1.37	$1.21 - $1.69
Q1 2025	1,856,526	$3,082	$1.65	$1.43 - $2.04
Q4 2024	3,210,290	$4,719	$1.53	$1.37 - $1.76
Q3 2024	2,501,674	$3,727	$1.48	$1.19 - $1.75
Q2 2024	344,333	$430	$1.30	$1.15 - $1.45
Q1 2024	223,386	$268	$1.00	$0.85 - $1.57
Q4 2023	408,551	$617	$1.45	$1.20 - $1.66
Q3 2023	209,591	$335	$1.82	$1.48 - $2.24
Q2 2023	179,604	$390	$1.56	$1.34 - $2.24
Q1 2023	264,227	$386	$1.29	$1.00 - $1.68
Q4 2022	1,075,629	$1,345	$1.58	$1.03 - $2.01
Q3 2022	850,208	$1,607	$2.36	$1.78 - $2.86
Q2 2022	1,046,418	$2,647	$2.92	$2.17 - $3.63
Q1 2022	296,618	$1,020	$3.53	$2.79 - $4.96
Q4 2021	828,065	$3,983	$4.05	$3.49 - $5.25
Q3 2021	211,672	$773	$3.72	$3.26 - $4.24
Q2 2021	291,931	$1,182	$3.92	$3.32 - $4.63
Q1 2021	280,020	$1,201	$4.78	$3.83 - $6.27
Q4 2020	176,440	$697	$4.18	$3.02 - $4.92
Q3 2020	1,110,217	$4,097	$4.22	$2.84 - $6.47
Q2 2020	7,843,629	$26,746	$2.24	$1.12 - $3.52
Q1 2020	62,568	$83	$1.57	$1.30 - $2.91
Q4 2019	147,490	$217	$1.67	$1.33 - $2.43
Q3 2019	231,655	$484	$2.04	$1.75 - $2.53
Q2 2019	243,630	$594	$2.18	$1.73 - $2.64
Q1 2019	2,150,527	$5,613	$3.03	$2.40 - $3.94
Q4 2018	448,207	$1,350	$3.39	$2.34 - $3.92
Q3 2018	553,220	$1,915	$5.26	$3.21 - $6.40
Q2 2018	451,434	$2,122	$3.79	$2.91 - $5.02
Q1 2018	346,821	$1,099	$4.03	$2.66 - $5.14
Q4 2017	458,032	$2,244	$5.80	$4.50 - $7.08
Q3 2017	58,321	$400	$6.31	$5.85 - $7.24
Q2 2017	141,238	$929	$7.01	$5.99 - $8.04
Q1 2017	45,342	$363	$8.42	$7.13 - $9.55
Q4 2016	197,801	$1,840	$10.35	$8.92 - $12.15
Q2 2016	324,644	$3,032	$10.16	$8.71 - $11.39
Q1 2016	55,142	$573	$9.14	$7.12 - $11.85
Q4 2015	352,641	$3,544	$10.02	$8.20 - $11.49
Q3 2015	1,319,616	$11,098	$13.24	$8.23 - $17.51
Q2 2015	347,443	$5,587	$15.55	$13.71 - $19.20
Q1 2015	91,434	$1,295	$13.01	$9.81 - $15.23
Q4 2014	287,782	$2,875	$8.56	$8.02 - $10.16
Q3 2014	110,889	$944	$8.79	$8.09 - $9.62
Q2 2014	180,415	$1,595	$8.73	$7.82 - $9.83
Q1 2014	4,772	$44	$8.77	$7.32 - $10.25
Q4 2013	6,998	$59	$10.11	$8.17 - $12.95
Q3 2013	115,440	$1,017	$8.02	$7.13 - $10.00
Q2 2013	18,281	$130	$6.91	$6.14 - $7.65