OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

Quantitative Investment Management, LLC's Holding History (CIK: 0001445911)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 127,100 Value ($000) $597 Avg Close $3.79 Range $2.91 - $5.02

Q3 2016

Shares 12,800 Value ($000) $135 Avg Close $9.96 Range $8.91 - $11.31

Q3 2015

Shares 299,800 Value ($000) $2,521 Avg Close $13.24 Range $8.23 - $17.51

Q1 2015

Shares 27,800 Value ($000) $393 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 35,800 Value ($000) $357 Avg Close $8.56 Range $8.02 - $10.16

Q1 2014

Shares 50,000 Value ($000) $466 Avg Close $8.77 Range $7.32 - $10.25

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	127,100	$597	$3.79	$2.91 - $5.02
Q3 2016	12,800	$135	$9.96	$8.91 - $11.31
Q3 2015	299,800	$2,521	$13.24	$8.23 - $17.51
Q1 2015	27,800	$393	$13.01	$9.81 - $15.23
Q4 2014	35,800	$357	$8.56	$8.02 - $10.16
Q1 2014	50,000	$466	$8.77	$7.32 - $10.25