OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 85,348 Value ($000) $108 Avg Close $1.39 Range $1.22 - $1.60

Q4 2024

Shares 66,282 Value ($000) $97 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 102,254 Value ($000) $152 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 36,542 Value ($000) $46 Avg Close $1.30 Range $1.15 - $1.45

Q3 2023

Shares 20,153 Value ($000) $32 Avg Close $1.82 Range $1.48 - $2.24

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	85,348	$108	$1.39	$1.22 - $1.60
Q4 2024	66,282	$97	$1.53	$1.37 - $1.76
Q3 2024	102,254	$152	$1.48	$1.19 - $1.75
Q2 2024	36,542	$46	$1.30	$1.15 - $1.45
Q3 2023	20,153	$32	$1.82	$1.48 - $2.24