OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 430,630 Value ($000) $543 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 392,761 Value ($000) $609 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 391,664 Value ($000) $517 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 201,345 Value ($000) $334 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 22,300 Value ($000) $33 Avg Close $1.53 Range $1.37 - $1.76

Q4 2023

Shares 1,538,716 Value ($000) $2,323 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 1,419,957 Value ($000) $2,272 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 1,092,121 Value ($000) $2,370 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 890,430 Value ($000) $1,300 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 818,624 Value ($000) $1,023 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 757,240 Value ($000) $1,431 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 524,622 Value ($000) $1,327 Avg Close $2.92 Range $2.17 - $3.63

Q4 2021

Shares 627,454 Value ($000) $3,018 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 989,130 Value ($000) $3,610 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 801,497 Value ($000) $3,246 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 119,825 Value ($000) $514 Avg Close $4.78 Range $3.83 - $6.27

Q1 2020

Shares 628,827 Value ($000) $843 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 642,008 Value ($000) $944 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 764,335 Value ($000) $1,597 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 702,735 Value ($000) $1,715 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 640,002 Value ($000) $1,670 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 741,241 Value ($000) $2,231 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 498,896 Value ($000) $1,726 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 210,782 Value ($000) $991 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 172,725 Value ($000) $548 Avg Close $4.03 Range $2.66 - $5.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	430,630	$543	$1.39	$1.22 - $1.60
Q3 2025	392,761	$609	$1.37	$1.11 - $1.55
Q2 2025	391,664	$517	$1.37	$1.21 - $1.69
Q1 2025	201,345	$334	$1.65	$1.43 - $2.04
Q4 2024	22,300	$33	$1.53	$1.37 - $1.76
Q4 2023	1,538,716	$2,323	$1.45	$1.20 - $1.66
Q3 2023	1,419,957	$2,272	$1.82	$1.48 - $2.24
Q2 2023	1,092,121	$2,370	$1.56	$1.34 - $2.24
Q1 2023	890,430	$1,300	$1.29	$1.00 - $1.68
Q4 2022	818,624	$1,023	$1.58	$1.03 - $2.01
Q3 2022	757,240	$1,431	$2.36	$1.78 - $2.86
Q2 2022	524,622	$1,327	$2.92	$2.17 - $3.63
Q4 2021	627,454	$3,018	$4.05	$3.49 - $5.25
Q3 2021	989,130	$3,610	$3.72	$3.26 - $4.24
Q2 2021	801,497	$3,246	$3.92	$3.32 - $4.63
Q1 2021	119,825	$514	$4.78	$3.83 - $6.27
Q1 2020	628,827	$843	$1.57	$1.30 - $2.91
Q4 2019	642,008	$944	$1.67	$1.33 - $2.43
Q3 2019	764,335	$1,597	$2.04	$1.75 - $2.53
Q2 2019	702,735	$1,715	$2.18	$1.73 - $2.64
Q1 2019	640,002	$1,670	$3.03	$2.40 - $3.94
Q4 2018	741,241	$2,231	$3.39	$2.34 - $3.92
Q3 2018	498,896	$1,726	$5.26	$3.21 - $6.40
Q2 2018	210,782	$991	$3.79	$2.91 - $5.02
Q1 2018	172,725	$548	$4.03	$2.66 - $5.14