ORCHESTRA BIOMED HLDGS INC

Ticker: OBIO CUSIP: 68572M106 Class: Common Stock

DAFNA Capital Management LLC's Holding History (CIK: 0001389933)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 126,841 Value ($000) $526 Avg Close $4.03 Range $2.42 - $5.42

Q3 2025

Shares 363,636 Value ($000) $902 Avg Close $2.76 Range $2.20 - $3.53

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	126,841	$526	$4.03	$2.42 - $5.42
Q3 2025	363,636	$902	$2.76	$2.20 - $3.53