OREXIGEN THERAPEUTICS INC

CUSIP: 686164104 Class: COMMON STOCK

Rock Springs Capital Management LP's Holding History (CIK: 0001595725)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 1,653,000 Value ($000) $711 Avg Close — Range —
Q1 2016
Shares 1,653,000 Value ($000) $930 Avg Close — Range —
Q4 2015
Shares 1,650,000 Value ($000) $2,838 Avg Close — Range —
Q3 2015
Shares 1,650,000 Value ($000) $3,482 Avg Close — Range —
Q2 2015
Shares 1,550,000 Value ($000) $7,673 Avg Close — Range —
Q1 2015
Shares 1,550,000 Value ($000) $12,137 Avg Close — Range —
Q4 2014
Shares 1,685,000 Value ($000) $10,211 Avg Close — Range —
Q3 2014
Shares 1,250,000 Value ($000) $5,325 Avg Close — Range —
Q2 2014
Shares 905,000 Value ($000) $5,593 Avg Close — Range —
Q1 2014
Shares 830,000 Value ($000) $5,395 Avg Close — Range —
Q4 2013
Shares 525,000 Value ($000) $2,956 Avg Close — Range —